TRIA, Giancarlo Fischers Allee 82 MOBILE (DE): +49 [0] 17 69

CURRICULUM VITAE
FORMATO EUROPEO/EUROPEAN FORMAT
INFORMAZIONI PERSONALI/
PERSONAL INFORMATION
Nome, Cognome/Name, Surname
Indirizzo/Address
Via, numero civico, c.a.p., città,
nazione/ House number, street
name, postcode, city, country
Telefono/Telephone
Fax
E-mail
Sito web/Website
Nazionalità/Nationality
Luogo e data di nascita/ Place and
Date of birth
TRIA, Giancarlo
Fischers Allee 82
22763 Hamburg
Germany
MOBILE (DE): +49 [0] 17 69 90 45 28 9
MOBILE (IT): +49 [0] 34 05 94 95 88
+49 [0] 40 89902 109
giancarlo.tria@gmail.com
http://www.embl-hamburg.de/biosaxs/tria.html
ITALIAN
Conversano (BA) – 25th August 1982
ESPERIENZA PROFESSIONALE/
WORK EXPERIENCE
Se dipendente CNR indicare:
In ordine di data /Dates (from – to)
Nome e indirizzo del datore di lavoro
/ Name and address of employer
Tipo o settore di attività / Type of
business or sector
Funzione o posto occupato /
Occupation or position held
Principali mansion e responsabilità /
Main activities and responsibilities
Page 1 - Curriculum vitae
di / of TRIA, Giancarlo
//
March 01st, 2009 - July 31st, 2010
Molecular Biodiversity LABoratory(MBLAB) - IBM Italy S.p.A. - Via Pietro Leonida Laforgia 14 70125 Bari
INDUSTRIAL RESEARCH
FULL TIME RESEARCHER
Research, design and development of bioinformatics tools for studies concerning molecular
biodiversity. In particular, I was involved in the design and development of software for the
prioritization of genes associated to Hereditary Hearing Loss disease. This project was
developed in collaboration with IRCCS CSS San Giovanni Rotondo – specialized centre for
Hereditary Hearing Loss condition. In details, the tool automatically evaluates the probability of
candidate genes to be associated to the pathology according to: biomedical literature,
GeneOntology products, sequence features, gene expression profiles and protein-protein
interaction.
ISTRUZIONE E FORMAZIONE /
EDUCATION AND TRAINING
In ordine di data /Dates (from – to)
Nome e tipo d’istituto di istruzione o
formazione / Name and type of
organisation providing education
and training
Principali materie e competenze
professionali apprese / Principal
subjects occupational skills covered
Certificato o diploma ottenuto /Title of
qualification awarded
Livello nella classificazione
nazionale o internazionale / Level in
National classification
In ordine di data /Dates (from – to)
Nome e tipo d’istituto di istruzione o
formazione / Name and type of
organisation providing education
and training
Principali materie e competenze
professionali apprese / Principal
subjects occupational skills covered
Certificato o diploma ottenuto /Title of
qualification awarded
Livello nella classificazione
nazionale o internazionale / Level in
National classification
In ordine di data /Dates (from – to)
Nome e tipo d’istituto di istruzione o
formazione / Name and type of
organisation providing education
and training
Principali materie e competenze
professionali apprese / Principal
subjects occupational skills covered
Certificato o diploma ottenuto /Title of
qualification awarded
Livello nella classificazione
nazionale o internazionale / Level in
National classification
Page 2 - Curriculum vitae
di / of TRIA, Giancarlo
August 16th, 2010 - (in progress) (expected to finish by end of April 2014)
European Molecular Biology Laboratory (EMBL) – Hamburg Outstation, DESY
campus, Notkestrasse 85, D-22603, Hamburg, Germany
Development of novel computational methods for constructing of 3D structural models of
macromolecules from Small Angle X-ray Scattering (SAXS) data. Special attention is given to
the joint use of SAXS with other structural, biophysical and biochemical techniques including
crystallography, NMR, electron microscopy, neutron scattering and bioinformatics for the study
of flexible macromolecules
BIOTECHNOLOGY RESEARCH
DOCTOR OF PHILOSOPHY (Ph.D.)
September 01st, 2008 - February 28th, 2009
Molecular Biodiversity LABoratory(MBLAB) - IBM Italy S.p.A. - Via Pietro Leonida Laforgia 14 70125 Bari
Advanced training of expert bioinformatics researchers for the studies concerning molecular
biodiversity
BIOINFORMATICS RESEARCH
INDUSTRIAL RESEARCHER
October 01st, 2006 - March 30th, 2010
UNIVERSITA’ DEGLI STUDI DI BARI - Via E. Orabona, 4 - 70125 Bari - Italy
Advanced training on Knowledge Base and Data mining, Knowledge Engineering and Artificial
Intelligence (with particular focus on practical application to biological data)
Master of Science in Computer Science
(with 110/110 and honours)
Second level degree – Master of Science
In ordine di data /Dates (from – to)
Nome e tipo d’istituto di istruzione o
formazione / Name and type of
organisation providing education
and training
Principali materie e competenze
professionali apprese / Principal
subjects occupational skills covered
Certificato o diploma ottenuto /Title of
qualification awarded
Livello nella classificazione
nazionale o internazionale / Level in
National classification
October 01st, 2003 – October 11th, 2006
UNIVERSITA’ DEGLI STUDI DI BARI - Via E. Orabona, 4 - 70125 Bari - Italy
Advanced training on Software Engineering and Technology for Software
Developing (with focus on all the aspects of software engineering)
Bachelor of Science in Computer Science and Technology for Software Developing
(with 110/110 and honours)
First level degree – Bachelor of Science
ATTIVITA’ DI RICERCA /
RESEARCH ACTIVITIES
Attuali campi di ricerca / Research
sectors
Small Angle X-ray Scattering (SAXS) in solution on Macromolecules
Recenti attività scientifiche/ Recent
Scientific Activities.
Development of dedicated software for the interpretation of SAXS data (ATSAS package)
with particular focus on experimental data from flexible particles
ULTERIORI INFORMAZIONI /
ADDITIONAL INFORMATION
Page 3 - Curriculum vitae
di / of TRIA, Giancarlo
Speaker in several courses and/or workshops dedicated (or related) to SAXS in solution on
macromolecules:
• BioSAXS 2014, February 22nd - 28th, 2014, University of Copenhagen, Denmark
• X-ray Diffraction and Bio-SAXS Core Facility of CEITEC – Inaugural workshop
September 12th - 13th, 2013, University Campus Bohunice, Brno, Czech Republic
• Practical course in Solution X-ray scattering data analysis – Application to Structural
Biology, August 5th - 14th, 2013, School of Biological Sciences, Nanyang Technological
University, Singapore
• SAXS and computational techniques to study intrinsically disordered proteins (IDPbyNMR
project), March 11th - 16th, 2013, EMBL Hamburg, Germany
• EMBO Practical Course on Solution Scattering From Biological Macromolecules
October 17th - 24th, 2012, EMBL Hamburg, Germany
Pubblicazioni/ Books and
Articles
Ilari A*, Alaleona F*, Tria G, Petrarca P, Battistoni A, Zamparelli C, Verzili D, Falconi M and
Chiancone E. (2013) The Salmonella enterica ZinT structure, zinc affinity and interaction with
the high-affinity uptake protein ZnuA provide insight into the management of periplasmic zinc.
Biochim Biophys Acta. 2013 Oct 12;1840(1):535-544. doi: 10.1016/j.bbagen.2013.10.010.
Møller M, Nielsen SS, Ramachandran S, Li Y, Tria G, Streicher, W, Petoukhov, M, Cerione, R,
Gillilan, R, and Vestergaard, B. (2013) Small Angle X-Ray Scattering Studies of Mitochondrial
Glutaminase C Reveal Extended Flexible Regions, and Link Oligomeric State with Enzyme
Activity. PLoS ONE 8(9): e74783. doi:10.1371/journal.pone.0074783
B. Sander, G. Tria, A. V. Shkumatov, E.-Y. Kim, J. G. Grossmann, I. Tessmer, D. I. Svergun and
H. Schindelin (2013) Structural characterization of gephyrin by AFM and SAXS reveals a mixture
of
compact
and
extended
states.
Acta
Cryst.
(2013).
D69,
2050-2060.
doi:10.1107/S0907444913018714
Koch C*, Tria G*, Fielding AJ, Brodhun F, Valerius O, Feussner K, Braus GH, Svergun DI,
Bennati M, Feussner I. (2013) A structural model of PpoA derived from SAXS-analysisImplications for substrate conversion. Biochim Biophys Acta. 2013 Sep;1831(9):1449-57. doi:
10.1016/j.bbalip.2013.06.003.
Petoukhov, M.V., Franke, D., Shkumatov, A.V., Tria, G., Kikhney, A.G., Gajda, M., Gorba, C.,
Mertens, H.D.T., Konarev, P.V. and Svergun, D.I. (2012) New developments in the ATSAS
program package for small-angle scattering data analysis. J. Appl. Cryst. 45, 342-350
Sachyani, D., Dvir, M., Strulovich, R., Tria, G., Pongs, O., Svergun, D. I., Attali, B., and Hirsch J.
A. 2014. "Structural Basis of a Kv7.1 (KCNQ1) Potassium Channel Gating Module: Studies of
the Intracellular C- terminal Domain in Complex with Calmodulin". (under review)
Soykan, T., Schneeberger, D., Tria, G., Bader, N., Svergun, D. I., Tessmer, I., Poulopoulos, A.,
Papadopoulos, T., Varoqueaux, F., Schindelin, H. and Buechner, C. N. 2014. "A Conformational
Switch in Collybistin Determines the Differentiation of Inhibitory Postsynapses". (under review)
Giancarlo Tria, Dmitri I Svergun and Pau Bernadó: Use of Ensemble Methods to Describe Biomolecular Dynamics by Small Angle X-ray Scattering. In Computational Approaches to Protein
Dynamics From Quantum to Coarse-Grained Methods. Edited by Taylor&Fracis (in press)
(chapter in book)
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di / of TRIA, Giancarlo
TRATTAMENTO DEI DATI
PERSONALI, INFORMATIVA E
CONSENSO
Il D.Lgs. 30/6/2003, n. 196 “Codice in materia di protezione dei dati personali” regola il
trattamento dei dati personali, con particolare riferimento alla riservatezza, all’identità personale
e al diritto di protezione dei dati personali; l’interessato deve essere previamente informato del
trattamento .
La norma in considerazione intende come “trattamento” qualunque operazione o complesso di
operazioni concernenti la raccolta, la registrazione, l’organizzazione, la conservazione, la
consultazione, l’elaborazione, la modifica, la selezione, l’estrazione, il raffronto, l’utilizzo,
l’interconnessione, il blocco, la comunicazione, la diffusione, la cancellazione e la distruzione di
dati, anche se non registrati in una banca dati.
In relazione a quanto riportato, autorizzo il CNR al trattamento dei dati contenuti nel presente
curriculum vitae e nella documentazione della quale fa parte integrante, sollevandolo da ogni
responsabilità e autorizzandolo alla pubblicazione, nel sito web del CNR, della relazione
inerente alle proprie ricerche svolte durante il soggiorno finanziato dal CNR nell’ambito del
Programma STM . Inoltre acconsento all’aggiornamento delle informazioni intranet che mi
riguardano sia relative le pubblicazioni sia alle ricerche svolte.
( barrare la casella)
Si, acconsento
Hamburg, 24/02/2014
(Giancarlo Tria)
Page 5 - Curriculum vitae
di / of TRIA, Giancarlo