Tuberculosis Vaccine Market - Latest Advancements & Market Outlook 2018 to 2026

Tuberculosis Vaccine Market
Global Industry Insights, Trends, Outlook, and
Opportunity Analysis, 2018–2026
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REPORT DESCRIPTION
Tuberculosis Vaccine Market Overview
Tuberculosis (TB) is a highly contagious disease caused by the bacterium known as
Mycobacterium tuberculosis and is mostly spread through person to person contact. It causes
multisystem infection and eventually might lead to death of the infected person. Two types of
TB that are commonly observed include latent TB in which the infected person do not show
symptoms and active TB in which the infected person shows clinical symptoms of TB. Clinical
symptoms and signs of TB include fever, night sweats, cough, weight loss, hemoptysis (coughing
up blood-stained sputum), fatigue, chest pain, and shortness of breath. Depending upon the
symptoms, TB may be classified as pulmonary TB, subcutaneous TB or military TB. Depending on
the resistance it shows, TB may be multidrug resistant TB or extended drug resistant TB.
Diagnosis of tuberculosis can be carried out using skin test, polymerase chain reaction test or
interferon-gamma release assays. Initial treatment regime for active TB includes drugs such as
ethambutol, pyrazinamide, isoniazid, and rifampicin. Although currently no TB vaccine is
approved commercially, children are vaccinated with BCG vaccine as a part of precautionary
measure. However, BCG vaccine has limited utility and variable efficacy in both adults and
children. Many TB vaccines are under the stage of clinical development, which are expected to
reach the market in the near future.
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REPORT DESCRIPTION
Tuberculosis Vaccine Market Dynamics
Tuberculosis account for the highest amount of death caused due to infectious disease
across the globe. According to the World Health Organization (WHO) factsheet 2018 on TB,
10.4 million people fell ill with TB in 2016 and 1.7 million people with TB died in the same
year. More than 95% of TB deaths occur in low- and middle-income economies. Deaths
caused due to TB also includes death of 0.4 million people infected with HIV. Such high
number of patients across the world confirms the enormity of disease and urgent
requirements for vaccines worldwide. Therefore, the launch of tuberculosis vaccine would
gain significant revenue and in turn, would propel the market growth. According to a global
report on tuberculosis vaccine in 2018, TB costs around US$ 21 billion annually to global
economy. Another important impetus to tuberculosis vaccine market would be current
complex drug regime and resistance TB has created to this drug regime. TB patient has to
take more than 2-3 drugs for prolonged time period of 6 months in order to suppress the
infection. Often this results in the poor patient compliance and eventually leads to drug
resistance incidence which further deteriorate the TB. According to WHO, there were nearly
600,000 new cases with resistance to rifampicin antibiotic, which was the most effective
first-line drug in 2017, of which around 490,000 had MDR-TB globally. If effective steps
won’t be taken by 2050, MDR-TB alone could cost the world US$ 16.7 trillion as per global
report on tuberculosis vaccine 2018. Drug toxicity due to high daily dose and prolonged
treatment is another concern with current TB drugs. Although the cost of TB drug is not
much of concern in developing economies due to government support and free medication,
it is a matter of concern in developed countries such as the U.S. and Europe
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REPORT DESCRIPTION
Tuberculosis Vaccine Market - Regional Insights
TB is most prevalent in middle and low income economies in Asia Pacific and Africa and
therefore, these regions would represent greatest opportunity for the potential TB vaccine.
According to the World Health Organization factsheet 2018 on TB, countries such as India,
China, Indonesia, Philippines, Pakistan, Nigeria, and South Africa account for around 64% of the
total TB deaths. Another risk factor for these regions is the high number of HIV positive
population living in this region. Around 40% of deaths among HIV-positive people were due to
TB in 2016 as per WHO. Tuberculosis vaccine could prove most beneficial for these regions and
in turn, would drive growth of tuberculosis vaccine market. Government initiatives and
international support to curb TB incidence would speed up the vaccine development and also
would support access for such vaccines.
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India, which accounts for half a million global TB deaths has launched National Strategic Plan
(NSP) for TB Elimination 2017-2025 to combat TB. India also formed India TB Research
Consortium to boost TB vaccine and medication research. Developed regions such as North
America accounts for significant number of TB patients. According to the Centre for Disease
Control, a total of 9,093 TB cases were reported in the U.S. in 2017. MDR-TB and XDR-TB
accounted for approximately US$ 160,000 and US$ 513,000 respectively for treatment of each
patient. Effective vaccine against TB would gain significant traction in countries such as the
U.S.
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Tuberculosis (TB) is a highly contagious disease caused by the bacterium known as Mycobacterium tuberculosis and is mostly spread through person to person contact. It causes multisystem infection and eventually might lead to death of the infected person. Two types of TB that are commonly observed include latent TB in which the infected person do not show symptoms and active TB in which the infected person shows clinical symptoms of TB. Clinical symptoms and signs of TB include fever, night sweats, cough, weight loss, hemoptysis (coughing up blood-stained sputum), fatigue, chest pain, and shortness of breath.