Spinal Muscular Atrophy Market

Spinal Muscular Atrophy Market
GLOBAL INDUSTRY INSIGHTS, TRENDS, OUTLOOK, AND
OPPORTUNITY ANALYSIS, 2018-2026
REPORT DESCRIPTION
Spinal Muscular Atrophy Market – Overview
The global spinal muscular atrophy market size was valued at US$ 884 million in 2017 and is expected to
witness a robust CAGR of 12.4% over the forecast period (2018–2026).
Spinal muscular atrophy (SMA) is a genetic disorder that affects the control of muscle movement. It is
caused due to loss of specialized nerve cells, called motor neurons, in the spinal cord and brainstem. The
loss of motor neurons leads to weakness and atrophy of muscles used for activities such as sitting up,
walking, crawling, and controlling head movement. In severe cases, the muscles used for swallowing and
breathing are also affected. There are four types of spinal muscular atrophy, which are differentiated based
on the severity of muscle weakness, pattern of features, and age, when the muscle problems begin. These
are classified as type 1, 2, and 3 that appears in childhood. Type 4 appears in adulthood and is also termed
as adult onset SMA.
REPORT DESCRIPTION
Spinal Muscular Atrophy Market Dynamics:
Major factors driving growth of the spinal muscular atrophy market includes increasing number of clinical
trials and rising government support for R&D. Biotechnology and biopharmaceutical companies are
working towards development of effective therapies to treat spinal muscular atrophy. For instance, in 2016,
the U.S. FDA approved Spinraza (nusinersen) drug from Biogen for the treatment of SMA. Spinraza targets
the underlying defect in SMA, so it can help prevent, delay, or even reverse the symptoms.
However, its common side effects include higher risk of constipation and respiratory tract infection along
with minimal risk of kidney problems and bleeding. Moreover, the cost of research for development of new
therapy is also high. With the advancements of drug in the pipeline, its expense and time for development
also increases. According to Cure SMA, it can take over 15 years and US$ 100 million for a single drug
candidate to reach FDA approval. These factors make research challenging particularly for a disease such
as SMA. These factors are expected to hinder growth of the market.
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REPORT DESCRIPTION
Spinal Muscular Atrophy Market – Key Players
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Biogen
Cytokinetics, Inc.
F. Hoffmann-La Roche
Novartis AG
Pfizer Inc.
Ionis Pharmaceuticals, Inc
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The global spinal muscular atrophy market size was valued at US$ 884 million in 2017 and is expected to witness a robust CAGR of 12.4% over the forecast period (2018–2026).