Vascular Endothelial Growth Factor Antibodies Market Drivers, Insights Analysis to 2026

Vascular
Endothelial
Growth
Factor
(VEGF)
Antibodies Market Size, Share, Trend, Outlook,
Future Growth Analysis And Synthesis 2018 - 2026
Vascular Endothelial Growth Factor (VEGF) is a signal protein that helps in the formation of new blood
vessels through a process known as angiogenesis. Vascular endothelial growth factor is a part of several
pathological processes and researches are often carried out for the development of novel therapies using
these factors for diseases such as cancer. Normal functions of vascular endothelial growth factor includes
embryonic development, formation of new blood vessels, and as a bypass for a blocked vessel. However,
overexpression of VEGF often culminates into fatal disease such as cancerous cells. As solid tumors
require additional blood supply in order to keep functioning, the overexpression of VEGF serves that
purpose through angiogenesis. VEGF family has five members such as VEGF-A, VEGF-B, VEGF-C, VEGFD, and Placenta Growth Factor (PGF). Out of these growth factors, VEGF-A is responsible for
angiogenesis and processes associated with endothelial cells. VEGF-A binds to VEGF receptors on the
endothelial cells, which triggers a tyrosine kinase pathway leading to angiogenesis. VEGF-A has been
found to be associated with poor prognosis in various cancers, diabetic retinopathy, and age-related
macular degeneration. Therapeutic agents are developed to inhibit the transduction pathways of vascular
endothelial growth factor (VEGF). Drugs such as monoclonal antibodies against VEGF and tyrosine kinase
inhibitors inhibit the angiogenesis process and disease progression.
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Vascular Endothelial Growth Factor (VEGF) Antibodies Market Drivers
Rising prevalence of diseases such as cancer and macular degeneration is expected to boost growth of
the market over the forecast period. According to the American Cancer Society, in 2017, cancer was the
second most common cause of death in the U.S., which accounts for nearly 1 out of every 4 deaths.
Novel therapies such as monoclonal antibodies and angiogenesis inhibitors are highly specialized targeted
therapies, which directly targets the cancerous cells. The preference for targeted therapies is rising,
owing to the advantages (lesser side effects) offered by targeted therapies over conventional therapies
such as chemotherapy. Furthermore, robust pipeline of VEGF antibodies is expected to boost the market
growth over the forecast period. For instance, Brolucizumab (Alcon) is in phase 3 clinical trials, Abicipar
(Allergan Plc) is in phase 3 trials, and RG7716 (Genentech) is in phase 2 trials, all indicated for agerelated macular degeneration.
Vascular Endothelial Growth Factor (VEGF) Antibodies Market Insights
On the basis of region, North America and Europe are expected to show significant growth in the
vascular endothelial growth factor antibodies market over the forecast period. North America has the
presence of leading manufacturers who are indulged in research and development of these therapies.
Manufacturers such as Novartis (Europe) and Genentech have these therapies in pipeline and are
expected to enter into the market over the forecast period. Asia Pacific region is expected to show
modest growth, owing to high costs of these therapies and fairly low availability overall the region.
Sophisticated insurance facilities such as Medicaid and Medicare are not present in the developing
economies due to which patients cannot afford costly medical treatment in these regions. However,
insurance facilities are expected to drive growth of the market in North America.
Report includes chapters which deeply display the following deliverable about industry :
• Vascular Endothelial Growth Factor (VEGF) Antibodies Market Research Objective and
Assumption
• Vascular Endothelial Growth Factor (VEGF) Antibodies Market Purview - Report Description,
Executive Summary, and Coherent Opportunity Map (COM)
• Vascular Endothelial Growth Factor (VEGF) Antibodies Market Dynamics, Regulations, and
Trends Analysis - Market Dynamics, Regulatory Scenario, Industry Trend, Merger and
Acquisitions, New system Launch/Approvals, Value Chain Analysis, Porter’s Analysis, and PEST
Analysis
• Global Vascular Endothelial Growth Factor (VEGF) Antibodies Market, By Regions
• Vascular Endothelial Growth Factor (VEGF) Antibodies Market Competition by Manufacturers
including Production, Share, Revenue, Average Price, Manufacturing Base Distribution, Sales
Area and Product Type.
• Vascular Endothelial Growth Factor (VEGF) Antibodies Market Manufacturers Profiles/Analysis
including Company Basic Information, Manufacturing Base and Its Competitors.
• Vascular Endothelial Growth Factor (VEGF) Antibodies Market Manufacturing Cost Analysis
including Key Raw Materials and Key Suppliers of Raw Materials.
• Industrial Chain, Sourcing Strategy and Downstream Buyers including Upstream Raw Materials
Sourcing and Downstream Buyers
• Marketing Strategy Analysis, Distributors/Traders including Marketing Channel, Market
Positioning and Distributors/Traders List.
• Market Effect Factors Analysis including Technology Progress/Risk, Consumer Needs/Customer
Preference Change and Economic/Political Environmental Change.
• Vascular Endothelial Growth Factor (VEGF) Antibodies Market Forecast including Production,
Consumption, Import and Export Forecast by Type, Applications and Region.
• Research Findings and Conclusion
Vascular Endothelial Growth Factor (VEGF) Antibodies Market – Key Players
Key players operating in the vascular endothelial growth factor (VEGF) antibodies market include
Genentech, Inc., Novartis, Exelixis, Inc., Eli Lilly and Company, Bayer Pharma AG, Regeneron
Pharmaceuticals, Inc., Valeant Pharmaceuticals, Ceres Oncology Pty Ltd, and ThromboGenics, Inc.
Vascular Endothelial Growth Factor (VEGF) Antibodies Market Taxonomy
The global vascular endothelial growth factor (VEGF) antibodies market is segmented on the basis of
drug, route of administration, application, distribution channel, and geography.
By Drug -
•
Avastin
•
Tecentriq
•
Cometriq
•
Eylea
•
Jetrea
•
Cyramza
•
Macugen
•
Lucentis
•
Others
By Application-
•
Cancer
•
Ophthalmology
•
Others
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Rising prevalence of diseases such as cancer and macular degeneration is expected to boost growth of the market over the forecast period.