NEGLECTED TROPICAL DISEASES Figure A.8.3. Reported number of people requiring interventions against NTDs, by country, 2014a SDG Target 3.3 By 2030, end the epidemics of AIDS, tuberculosis, malaria and neglected tropical diseases and combat hepatitis, water-borne diseases and other communicable diseases Indicator 3.3.5: Number of people requiring interventions against neglected tropical diseases SITUATION Key interventions against neglected tropical diseases (NTDs) include mass treatment; individual treatment and care; water, sanitation and hygiene (WASH); vector control; and veterinary public health, as well as supportive interventions to strengthen health systems. The end of the epidemic will be first evidenced by reductions in the number of people requiring mass or individual treatment and care, as diseases are eliminated or controlled. Treatment and care are the interventions covered in this section. Some of the other wide-ranging interventions listed above can be addressed by SDG targets and indicators for UHC (Target 3.8) and access to water and sanitation (Targets 6.1 and 6.2). NTDs: lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminthiases (STH) and trachoma. More than 2.7 million people needed individual treatment and care for other NTDs such as Buruli ulcer, dengue, guinea-worm disease, human African trypanosomiasis (HAT), leprosy, the leishmaniases and yaws (Fig. A.8.2). ACHIEVING THE 2030 TARGET In 2014, 50 countries had achieved national elimination or were under surveillance for elimination of at least one NTD. For example, the number of people requiring mass treatment for lymphatic filariasis has decreased from a high of 1.4 billion in 2011 to 1.1 billion in 2014. In 2014, at least 1.7 billion people required mass or individual treatment and care for NTDs in 185 countries.1 Of these, 1.1 billion were in lower-middle-income countries (Fig. A.8.1). The 520 million people requiring treatment in low-income countries represented 60% of their populations. For NTDs targeted for elimination or eradication in World Health Assembly (WHA) resolutions,2 ending the epidemic implies a reduction in the number of people requiring treatment and care towards zero. The control of other NTDs means a reduction in the frequency of intervention. Taken together, existing WHA-endorsed targets should lead to a 90% reduction in the average number of people requiring treatment and care per year. Almost all of these 1.7 billion people required mass treatment for at least one of the following Reducing the number of people requiring treatment and care does not depend solely Figure A.8.1. Reported number of people requiring interventions against NTDs, by country income group, 2014a Lower middle income Low income Upper middle income High income l 10 l 100 l 1000 l 10 000 l 100 000 Number in thousands (logarithmic scale) Horizontal line reflects 95% uncertainty intervals around missing values in 2014. a Figure A.8.2. Reported number of people requiring interventions against NTDs, by disease, 2014a,b l 1 000 000 on the actions of the health sector: controlling STH requires universal access to water and sanitation; controlling dengue requires vector control as an adaptive response to urbanization and climate change. Disaggregation by disease will be an important element in monitoring successes and failures. EQUITY People requiring interventions against NTDs are poor and marginalized. Monitoring NTDs and intervention coverage is therefore key to ensuring that the least well off are prioritized from the beginning of the path towards UHC and universal access to safe water and sanitation.3,4 Indeed, NTD monitoring can help the health and WASH sectors to achieve their universal access goals by better targeting the poorest and most marginalized populations. DATA GAPS Gaps in NTD reporting systems include the number of people requiring treatment and care for dengue in the WHO African Region, for Chagas disease and for zoonotic NTDs, as well as the number of new cases requiring and requesting surgery or rehabilitation. Based on reporting systems for donated medicines, data disaggregation by sex and by urban or rural area is optional or dependent upon which diseases are co-endemic. Some disaggregation by age is available. Figures A.8.1 to A.8.3 present conservative estimates of the number of people requiring treatment and care for NTDs, assuming perfect co-endemicity of some NTDs at the level of the smallest available unit and age group. By 2030, improved co-endemicity data and models will be used to validate this approach. Any changes over time in case detection rates will have to be taken into account when making comparisons to the baseline. REFERENCES Unless otherwise noted, all statistics in the text and figures are taken from: Global Health Observatory [website]. Geneva: World Health Organization (http://www.who.int/gho/en/), and the Preventive Chemotherapy and Transmission Control (PCT) databank. Geneva: World Health Organization (http://www.who.int/neglected_diseases/preventive_chemotherapy/ databank/en/). 1 Eradication of guinea-worm disease (2015) and yaws (2020); global elimination of leprosy (2020), lymphatic filariasis (2020), trachoma (2020), onchocerciasis (2025) and HAT (2020, with zero incidence in 2030); regional elimination of schistosomiasis (2020), rabies (2020) and visceral leishmaniasis (2020); regional interruption of intra-domiciliary transmission of Chagas disease (2020). 2 Tracking universal health coverage: first global monitoring report. Geneva and Washington (DC): World Health Organization and World Bank; 2015 (http://www.who.int/healthinfo/universal_health_coverage/ report/2015/en/, accessed 25 March 2016). 3 Horizontal lines reflect 95% uncertainty intervals around missing values in 2014. a Data for dengue are not available from the WHO African Region; data for echinococcosis are available from some countries of the WHO European Region only; data for other NTDs including Chagas disease and zoonotic NTDs are not currently available. b 58 WORLD HEALTH STATISTICS: 2016 a Horizontal lines reflect 95% uncertainty intervals around missing values in 2014. A country is shown as not having available data when the uncertainty interval exceeds two orders of magnitude. Water sanitation & hygiene for accelerating and sustaining progress on neglected tropical diseases. A global strategy 2015–2020. Geneva: World Health Organization; 2015 (http://www.who.int/water_sanitation_health/ publications/wash-and-ntd-strategy/en/, accessed 29 March 2015). 4 MONITORING HEALTH FOR THE SDGs 59
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