Curriculum Vitae (April, 2016) Gordon L. Warren III, Ph.D. Distinguished University Professor Office Mailing Address: Department of Physical Therapy P.O. Box 4019 Georgia State University Atlanta, Georgia 30302–4019 Office Phone Number: (404) 413-1255 Office Email Address: gwarren@gsu.edu Education: 1976-1980 Georgia Institute of Technology Atlanta, Georgia B.S. (Nuclear Engineering) GPA: 3.7 1984-1986 Massachusetts Institute of Technology Cambridge, Massachusetts M.S. (Radiological Sciences/Biomedical Engineering) GPA: 5.0 (out of 5) Thesis: Gated blood flow measurement in the canine myocardium using positron-computed tomography 1986-1989 University of Georgia Athens, Georgia Ph.D. (Exercise Physiology) GPA: 4.0 Dissertation: The role of diffusion limitation in exercise-induced hypoxemia Academic Experience: 2013-present Distinguished University Professor (tenured) Department of Physical Therapy Byrdine F. Lewis School of Nursing and Health Professions Georgia State University Atlanta, Georgia 2005-2013 Professor (tenured) Department of Physical Therapy Byrdine F. Lewis School of Nursing and Health Professions Georgia State University Atlanta, Georgia 2005-present Adjunct Professor School of Applied Physiology Georgia Institute of Technology Atlanta, Georgia 1998-2005 Associate Professor Department of Physical Therapy Georgia State University Atlanta, Georgia Responsible for developing and teaching the research methodology sequence of courses (PT 7600, PT 7700 (or PT 8500), PT 8600, and PT 8800) in the doctor of physical therapy (DPT) curriculum in addition to teaching exercise physiology (PT 6910) and musculoskeletal pathophysiology (PT 6700) to the 1st year DPT students. The PT 6910 course focuses on the biochemical and nutritional aspects of acute and chronic exercise. Research focus is a continuation of that described below for 1990-1998. More recent research efforts have focused on: 1) how cellular- and molecular-level inflammatory processes modulate the functional recovery following traumatic and exercise/workinduced musculoskeletal injuries, 2) how aging and loss of estrogen in females modulate muscle strength and recovery from traumatic muscle injury, and 3) how adjacent tissues (i.e., muscle and bone) affect the other’s recovery from traumatic wounds mimicking those occurring on the battlefield. Other Professional Experience: 1993-1998 Research Scientist and Assistant Director, Muscle Biology Laboratory Texas A&M University College Station, TX Supervised daily operations of the laboratory as well as planned and executed the laboratory's long-term research plan. Co-taught a senior-level exercise physiology course for one semester as well as graduate-level muscle mechanics and histochemistry labs for three years. Supervised two post-doctoral fellows, one graduate student, one undergraduate student, and one research technician. Research focus was a continuation of that described below for the years 1990-1992. Directed studies concerned with determining: 1) muscle:bone mechanical inter-relationships and how specific muscle training and estrogen affect those relationships, 2) the structural sites of failure associated with the loss of excitation-contraction coupling resulting from eccentric muscle contractions, 3) the effect of eccentric contractions on localized and whole fiber free cytosolic calcium concentrations while at rest and during tetanic contractions, 4) the effect of protein metabolism on muscle function following the initiation of eccentric contractioninduced injury and the relationship of phagocytic cells to the protein metabolism, 5) the effect of injurious eccentric contractions on muscle basal metabolic rate and contractile energetic costs and how mitochondria respond to the insult, and 6) the neural contribution to the adaptation that occurs following a bout of injurious eccentric contractions. 1992-1993 Assistant Director Muscle Biology Laboratory University of Georgia Athens, Georgia Taught two doctoral-level courses in exercise biochemistry and muscle physiology. Supervised daily operations of the laboratory as well as planned and executed the laboratory's long-term research plan. Research focus was a continuation of that described below for the years 1990-1992. Directed studies concerned with: 1) determining the influence of fiber type and chronic activity on a muscle’s susceptibility to eccentric contraction-induced injury and 2) the effect of contractile activity on plasmalemma and T-tubular membranes as determined using confocal laser scanning microscopy. 1990-1992 Post-Doctoral Research Associate Muscle Biology Laboratory University of Georgia Athens, Georgia Directed studies investigating work/exercise-induced muscle fiber injury; these studies focused on the initiating event(s) and the early degenerative processes. Emphasis was placed on the contribution of mechanical factors and the calcium-mediated processes. Specific aims included: 1) to test the hypothesis that muscle fiber injury occurs in skeletal muscles as a function of the specific tension imposed on the fibers; 2) to test the hypothesis that these high mechanical forces cause disruption of the normal permeability barrier provided by the sarcolemma; 3) to test the hypothesis that an elevation in intracellular calcium concentration resulting from the disruption to sarcolemma is a critical step in the exercise-induced muscle fiber pathology; and 4) to test the hypothesis that activation of the phospholipase A2 pathway in the muscle fibers by elevated intracellular calcium, with associated production of arachidonic acid and its metabolites, plays a central role in the etiology of work/exercise-induced muscle fiber injury. 1987-1989 Research Assistant Exercise Physiology Laboratory University of Georgia Athens, Georgia Carried out studies concerned with determining: 1) gender differences in peak oxygen consumption during arm and leg exercise; 2) the impairment of lung function during a 24-hour ultramarathon; and 3) the contribution of pulmonary diffusion limitation to the exercise-induced arterial hypoxemia observed in elite endurance athletes. 1985-1986 Research Associate Physics Research Laboratory Massachusetts General Hospital Boston, Massachusetts Developed a myocardial blood flow measurement technique utilizing positron emission tomography. Technique was utilized in cardiac allograft rejection detection and characterization studies at Massachusetts General Hospital. 1984-1985 Teaching Assistant Nuclear Engineering Department Massachusetts Institute of Technology Cambridge, Massachusetts Assisted in instruction of graduate level courses in nuclear physics and engineering thermodynamics. 1982-1984 Captain; Assistant Brigade Logistics Officer Corps of Engineers U.S. Army Fort Bragg, North Carolina Managed the $6.7 million (2014 $) equipment and materials budget of the 18th Airborne Corps’ engineer brigade. Responsible for fielding of all new tactical systems to the brigade and automation of the budget and supply activities at the brigade and subordinate unit levels. Oversaw and conducted logistical deployment to Grenada. 1980-1982 Lieutenant; Platoon Leader Corps of Engineers U.S. Army Fort Bragg, North Carolina Responsible for the training and welfare of an 82nd Airborne Division 34-man airborne (parachute) combat engineer platoon in support of worldwide, no-notice, 18-hour deployment requirements. Selected for special staff position as battalion engineer for an airborne infantry battalion. Oversaw and conducted deployments to the Middle East, Panama, and El Salvador. Publications: Journal Articles (published; all refereed) (As of May 2016, these 83 articles have been cited 6139 times in the peer-reviewed literature according to Google Scholar.) Willett, N.J., L. Krishnan, M.T. Li, R.E. Guldberg, and G.L. Warren. Guidelines for models of skeletal muscle injury and therapeutic assessment. Cells Tissues Organs. In press. Warren, G.L., J.A. Call, A.K. Farthing, and B. Baadom-Piaro. Minimal evidence for a secondary loss of strength after an acute muscle injury: A systematic review and meta-analysis. Sports Med. Epub ahead of prin. DOI: 10.1007/s40279-016-0528-7. Collier, N.B., M.A. Hardy, M.L. Millard-Stafford, and G.L. Warren. Small beneficial effect of caffeinated energy drink ingestion on strength. J. Strength Cond. Res. Epub ahead of print. DOI: 10.1519/JSC.0000000000001289. Henes, S.T., A. Johnson, M. Toner, K. Mamaril, M. Kelkar, Y. Xiao, and G.L. Warren. Assessing resting metabolic rate in overweight and obese adolescents with a portable indirect calorimeter: A pilot study for validity and reliability. Nutr. Clin. Pract. 31: 355-361, 2016. Morelli, K.M., J.D. Garcia, L.B. Brown, A.K. Farthing, J.L. Miller, and G.L. Warren. Clinical measures predicting knee extensor muscle activation during a maximal voluntary isometric contraction. J. Exerc. Sports Orthop. 3: 1-10, 2016. Morelli, K.M., M. Carrelli, M.A. Nunez, C. Smith, and G.L. Warren. Addition of hip exercises to treatment of patellofemoral pain syndrome: A meta-analysis. World J. Meta-Anal. 3: 118-124, 2015. Novotny, S.A., G.L. Warren, and M.W. Hamrick. Aging and the muscle-bone relationship. Physiology. 30: 8-16, 2015. Mader, T.L., S.A. Novotny, A.S. Lin, R.E. Guldberg, D.A. Lowe, and G.L. Warren. CCR2 elimination in mice results in larger and stronger tibial bones but bone loss is not attenuated after ovariectomy or denervation. Calc. Tissue Int. 95: 457-466, 2014. Novotny, S.A., T.L. Mader, A.G. Greising, A.S. Lin, R.E. Guldberg, G.L. Warren, and D.A. Lowe. Low intensity, high frequency vibration training to improve musculoskeletal function in a mouse model of Duchenne muscular dystrophy. PloS One. 9:e104339. doi: 10.1371/journal.pone.0104339, 2014. Chen, Y.P., S. Pope, D. Tyler, and G.L. Warren. Effectiveness of constraint-induced movement therapy on upperextremity function in children with cerebral palsy: A systematic review and meta-analysis of randomized controlled trials. Clin. Rehab. 10: 938-953, 2014. Li, M.T., N.J. Willett, B.A. Uhrig, R.E. Guldberg, and G.L. Warren. Functional analysis of limb recovery following autograft treatment of volumetric muscle loss in the quadriceps femoris. J. Biomech. 47: 2013-2021, 2014. Call, J.A., G.L. Warren, M. Verma, and D.A. Lowe. Acute failure of action potential conduction in mdx muscle reveals new mechanism of contraction-induced force loss. J. Physiol. 591: 3765-3776, 2013. Willett, N.J.,M.A. Li, B.A. Uhrig, J.D. Boerckel, G.L. Warren, and R.E. Guldberg. Attenuated BMP-2 mediated bone regeneration in a rat model of composite bone and muscle injury. Tissue Eng. Part C Methods. 19: 316-325, 2013. Sawyer, A.M., S.K. Martinez, and G.L. Warren. Impact of yoga on low back pain and function: a systematic review and meta-analysis. J. Yoga Phys. Ther. 2:120, 2012. doi:10.4172/2157-7595.1000120 Novotny, S.A., G.L. Warren, A.S. Lin, R.E. Guldberg, K.A. Baltgalvis, and D.A. Lowe. Prednisolone treatment and restricted physical activity further compromise bone of mdx mice. J. Musculoskelet. Neuronal Interact. 12:16-23, 2012. Call, J.A., M.D. Eckhoff, K.A. Baltgalvis, G.L. Warren, and D.A. Lowe. Adaptive strength gains in dystrophic muscle exposed to repeated bouts of eccentric contraction. J. Appl. Physiol. 111: 1768-1777, 2011. Kressler, J., M. Millard-Stafford, and G.L. Warren. Quercetin improves endurance exercise capacity: a systematic review and meta-analysis. Med. Sci. Sports Exerc. 43: 2396-2404, 2011. Warren, G.L., T. Hulderman, A. Liston, and P.P. Simeonova. Toll-like and adenosine receptor expression in injured skeletal muscle. Muscle Nerve. 44: 85-92, 2011. Novotny, S.A., G.L. Warren, A.S. Lin, R.E. Guldberg, K.A. Baltgalvis, and D.A. Lowe. Bone is functionally impaired in dystrophic mice but less so than skeletal muscle. Neuromuscul. Disorders. 21: 183-193 2011. Conger, S.A., G.L. Warren, M.A. Hardy, and M.L. Millard-Stafford. Does caffeine added to carbohydrate provide additional ergogenic benefit for endurance? Int. J. Sport Nutr. Exerc. Metab. 21: 71-84, 2011. Greising, S.M., K.A. Baltgalvis, A.M. Kosir, A.L. Moran, G.L. Warren, and D.A. Lowe. Estradiol’s beneficial effect on murine muscle function is independent of muscle activity. J. Appl. Physiol. 110: 109-115, 2011. Walker, T.B., U. Balldin, J. Fischer, W. Storm, and G.L. Warren. Acceleration tolerance after ingestion of a commercial energy drink. Aviat. Space Environ. Med. 81: 1100-1106, 2010. Urso, M.L., E.R. Szelenyi, G.L. Warren, and B.R. Barnes. Matrix metalloprotease-3 and tissue inhibitor of metalloprotease-1 mRNA and protein levels are altered in response to traumatic skeletal muscle injury. Eur. J. Appl Physiol. 109: 963-72, 2010. Wenke, J.C., G.L. Warren, C.R. Rathbone, and R.B. Armstrong. Planter flexor muscle size and strength after inactivity and training. Aviat. Space Environ. Med., 81: 632-638, 2010. Warren, G.L., N.D. Park, R.D. Maresca, K.I. McKibans, and M.L. Millard-Stafford. Effect of caffeine ingestion on muscular strength and endurance: a meta-analysis. Med. Sci. Sports Exerc. 42: 1375-1387, 2010. Baltgalvis K.A., S.M. Greising, G.L. Warren, and D.A. Lowe. Estrogen regulates estrogen receptors in mouse skeletal muscle. PloS ONE. 5:e10164, 2010. Barnes, B.R., E.R. Szelenyi, G.L. Warren, and M.L. Urso. Alterations in mRNA and protein levels of matrix metalloproteases-2, -9 and -14 and tissue inhibitor of metalloprotease-2 in response to traumatic skeletal muscle injury. Am. J. Physiol: Cell Physiol. 297: C1501-C1508, 2009. Greising, S.M., K.A. Baltgalvis, D.A. Lowe, and G.L. Warren. Hormone therapy and skeletal muscle strength: a meta-analysis. J. Gerontol. A Biol. Sci. Med. Sci. 64: 1071-1081, 2009. Park, N.D., R.D. Maresca, K.I. McKibans, D.R. Morgan, T.S. Allen, and G.L. Warren. Caffeine’s beneficial effect on maximal voluntary strength and activation in uninjured but not injured muscle. Int. J. Sport Nutr. Exerc. Metab. 18: 639-652, 2008. Warren, G.L., A.L. Moran, H.A. Hogan, A.S. Lin, R.E. Guldberg, and D.A. Lowe. Voluntary run training but not estradiol deficiency alters the tibial bone-soleus muscle functional relationship in mice. Am. J. Physiol: Regul. Integr. Comp. Physiol. 293: R2015-R2026, 2007. Warren, G.L., M. Summan, X. Gao, R. Chapman, T. Hulderman, and P.P. Simeonova. Mechanisms of skeletal muscle injury and repair revealed by gene expression studies in mouse models. J. Physiol. 582: 825-841, 2007. Millard-Stafford, M.L., K.J. Cureton, J.E. Wingo, J. Trilk, G.L. Warren, and M. Buyckx. Hydration during exercise in the heat: effect of a caffeinated sports drink. Int. J. Sport Nutr. Exerc. Metab. 17: 163-177, 2007. Moran, A.L., S.A Nelson, R.M. Landisch, G.L. Warren, and D.A. Lowe. Estradiol replacement reverses ovariectomy-induced muscle contractile and myosin dysfunction in mature female mice. J. Appl. Physiol. 102: 13871393, 2007. Cureton, K.J., G.L. Warren, M.L. Millard-Stafford, J.E. Wingo, J. Trilk, and M. Buyckx. Caffeinated sports drink: ergogenic effects and possible mechanisms. Int. J. Sport Nutr. Exerc. Metab. 17: 35-55, 2007. Warren, G.L., L. O'Farrell, K.R. Rogers, K.M. Billings, S.P. Sayers, and P.M. Clarkson. CK-MM autoantibodies: prevalence, immune complexes, and effect on CK clearance. Muscle Nerve 34: 335-346, 2006. Summan, M., G.L. Warren, R. Mercer, R. Chapman, T. Hulderman, N. Van Rooijen, and P.P. Simeonova. Macrophages and skeletal muscle regeneration: a clodronate-containing liposome depletion study. Am. J. Physiol: Regul. Integr. Comp. Physiol. 290: R1488-R1495, 2006. Moran, A.L., G.L. Warren, and D.A. Lowe. Removal of ovarian hormones from mature mice detrimentally affects muscle contractile function and myosin structural distribution. J. Appl. Physiol. 100: 548-559, 2006. Moran, A.L., G.L. Warren, and D.A. Lowe. Soleus and EDL muscle contractility across the lifespan of C57BL/6 mice. Exp. Gerontol. 40: 966-975, 2005. Millard-Stafford, M., G.L. Warren, L.M. Thomas, J.A. Doyle, T. Snow, and K. Hitchcock. Recovery from run training: efficacy of a carbohydrate-protein beverage? Int. J. Sport Nutr. Exerc. Metab. 15: 610-624, 2005. Warren, G.L., T. Hulderman, D. Mishra, X. Gao, L. O’Farrell, W.A. Kuziel, and P.P. Simeonova. Chemokine receptor CCR2 involvement in skeletal muscle regeneration. FASEB J Epub: 10.1096/fj.04-2421fje. Summary version in print: 19: 413-415, 2005. Warren, G.L., J.L. Stallone, M.R. Allen, and S.A. Bloomfield. Functional recovery of the plantarflexor muscle group after hindlimb unloading in the rat. Eur. J. Appl. Physiol. 93: 130-138, 2004. Ingalls, C.P., G.L. Warren, J.Z. Zhang, S. Hamilton, and R.B. Armstrong. Dihydropyridine and ryanodine receptor binding after eccentric contractions in mouse skeletal muscle. J. Appl. Physiol. 96: 1619-1625, 2004. Warren, G.L., L. O’Farrell, T. Hulderman, D. Mishra, M. Summan, M.I. Luster, W.A. Kuziel, and P.P. Simeonova. Role of CC chemokines in skeletal muscle functional restoration after injury. Am. J. Physiol: Cell Physiol. 286: C1031-C1036, 2004. Bickel, C.S., J.M. Slade, L.R. VanHiel, G.L. Warren, and G.A. Dudley. Variable frequency train stimulation of skeletal muscle after spinal cord injury. J. Rehabil. Res. Dev. 41: 33-40, 2004. Warren, G.L., R.M. Maher, and E.J. Higbie. Temporal patterns of plantar pressures and lower-leg muscle activity during walking: effect of speed. Gait Posture. 19: 97-106, 2004. Lowe, D.A., G.L. Warren, L.M. Snow, L.V. Thompson, and D.D. Thomas. Muscle activity and aging affect myosin structure and function in rat fibers. J. Appl. Physiol. 96: 498-506, 2004. Rathbone, C.R., J.C. Wenke, G.L. Warren, and R.B. Armstrong. Importance of satellite cells in the recovery of strength after eccentric contraction-induced muscle injury. Am. J. Physiol: Regul. Integr. Comp. Physiol. 285: R1490R1495, 2003. Summan, M., M. McKinstry, G.L. Warren, T. Hulderman, K. Brumbaugh, M.I. Luster, and P.P. Simeonova. Inflammatory mediators and skeletal muscle injury: A cDNA microarray analysis. J. Interferon Cytokine Res. 23: 237246, 2003. Bickel, C.S., J.M. Slade, G.L. Warren, and G.A Dudley. Fatigability and variable frequency train stimulation of human skeletal muscles. Phys. Ther. 83: 366-373, 2003. Slade, J.M., C.S. Bickel, G.L. Warren, and G.A Dudley. Variable frequency trains enhance torque independent of stimulation amplitude. Acta Physiol. Scand. 177: 87-92, 2003. Warren, G.L., T. Hulderman, N. Jensen, M. McKinstry, M. Mishra, M.I. Luster, and P.P. Simeonova. Physiological role of tumor necrosis factor-α in traumatic muscle injury. FASEB J. Epub: 10.1096/fj.02-0187fje, 2002. Summary version in print: 16:1630-2, 2002. Warren, G.L., C.P. Ingalls, and R.B. Armstrong. Temperature dependency of force loss and Ca2+ homeostasis in mouse EDL muscle after eccentric contractions. Am. J. Physiol: Regul. Integr. Comp. Physiol. 282: R1122-R1132, 2002. Warren, G.L., C.P. Ingalls, D.A. Lowe, and R.B. Armstrong. What mechanisms contribute to the strength loss that occurs during and in the recovery from skeletal muscle injury? J. Orthop. Sports Phys. Ther. 32: 58-64, 2002. Warren, G.L., C.P. Ingalls, D.A. Lowe, and R.B. Armstrong. Excitation-contraction uncoupling: major role in contraction-induced muscle injury. Exerc. Sports Sci. Rev. 29: 82-87, 2001. Kegley, K.M, J. Gephardt, G.L. Warren, and G.K. Pavlath. Altered primary myogenesis in NFAT4-/- mice leads to decreased muscle size. Dev. Biol. 232: 115-126, 2001. Saunders, M.J., E.M. Evans, S.A. Arngrimsson, G.W. Flowers, J.D. Allison, G.L. Warren, and K.J. Cureton. Muscle activation and slow component rise in oxygen uptake during cycling. Med. Sci. Sports Exerc. 32: 2040-2045, 2000. Warren, G.L., J.M. Fennessey, and M.L. Millard-Stafford. Strength loss after eccentric contractions is unaffected by creatine supplementation. J. Appl. Physiol. 89: 557-562, 2000. Warren, G.L., K.M. Hermann, C.P. Ingalls, M.R. Masselli, and R.B. Armstrong. Decreased EMG median frequency during a second bout of eccentric contractions. Med. Sci. Sports Exerc. 32: 820-829, 2000. Ingalls, C.P., G.L. Warren, and R.B. Armstrong. Intracellular Ca2+ transients in mouse soleus muscle after hindlimb unloading and reloading. J. Appl. Physiol. 87: 386-390, 1999. Inman, C.L., G.L. Warren, H.A. Hogan, and S.A. Bloomfield. Mechanical loading attenuates immobilization-induced reductions in bone mass and strength. J. Appl. Physiol. 87: 189-195, 1999. Warren, G.L., C.P. Ingalls, S. J. Shah, and R.B. Armstrong. Uncoupling of in vivo torque production from EMG in mouse muscles injured by eccentric contractions. J. Physiol (Lond.). 515: 609-619, 1999. Warren, G.L., D.A. Lowe, and R.B. Armstrong. Measurement tools used in the study of eccentric contraction-induced injury. Sports Med. 27: 43-59, 1999. Ingalls, C.P., G.L. Warren, J.H. Williams, C.W. Ward, and R.B. Armstrong. E-C coupling failure in mouse EDL muscle after in vivo eccentric contractions. J. Appl. Physiol. 85: 58-67, 1998. Warren, G.L., C.P. Ingalls, and R.B. Armstrong. A stimulating nerve cuff for chronic in vivo measurements of torque produced about the ankle in the mouse. J. Appl. Physiol. 84: 2171-2176, 1998. Ingalls, C.P., G.L. Warren, and R.B. Armstrong. Dissociation of force production from MHC and actin contents in muscles injured by eccentric contractions. J. Muscle Res. Cell Motil. 19: 215-224, 1998. Warren, G.L., J.H. Williams, C.W. Ward, H. Matoba, C.P. Ingalls, K.M. Hermann, and R.B. Armstrong. Decreased contraction economy in mouse EDL muscle injured by eccentric contractions. J. Appl. Physiol. 81: 2555-2564, 1996. Higbie, E.J., K.J. Cureton, G.L. Warren, and B.M. Prior. Effects of concentric and eccentric training on muscle strength, cross-sectional area and neural activation. J. Appl. Physiol. 81: 2173-2181, 1996. Warren, G.L., D.A. Lowe, C.L. Inman, O.M. Orr, H.A. Hogan, S.A. Bloomfield, and R.B. Armstrong. Estradiol effect on anterior crural muscles:tibial bone relationship and susceptibility to injury. J. Appl. Physiol. 80: 1660-1665, 1996. White-Welkley, J.E., G.L. Warren, B.N. Bunnell, E.H. Mougey, J.L. Meyerhof, and R.K. Dishman. Treadmill exercise training and estradiol increase plasma levels of ACTH and prolactin after heterotypic stress. J. Appl. Physiol. 80: 931-939, 1996. Ingalls, C.P., G.L. Warren, D.A. Lowe, D.B. Boorstein, and R.B. Armstrong. Differential effects of anesthetics on in vivo skeletal muscle contractile function in the mouse. J. Appl. Physiol. 80: 332-340, 1996. Warren, G.L., D.A. Lowe, D.A. Hayes, M.A. Farmer, and R.B. Armstrong. Redistribution of cell membrane probes following contraction-induced injury of mouse soleus muscle. Cell Tissue Res. 282: 311-320, 1995. Lowe, D.A., G.L. Warren, C.P. Ingalls, D.B. Boorstein, and R.B. Armstrong. Muscle function and protein metabolism following initiation of eccentric contraction-induced injury. J. Appl. Physiol. 79: 1260-1270, 1995. Warren, G.L., D.A. Hayes, D.A. Lowe, J.H. Williams, and R.B. Armstrong. Eccentric contraction-induced injury in normal and hindlimb-suspended mouse soleus and EDL muscles. J. Appl. Physiol. 77: 1421-1430, 1994. Lowe, D.A., G.L. Warren, D.A. Hayes, M.A. Farmer, and R.B. Armstrong. Eccentric contraction-induced injury of mouse soleus muscle: effect of varying [Ca2+]o. J. Appl. Physiol. 76: 1445-1453, 1994. Warren, G.L., D.A. Lowe, D.A. Hayes, C.J. Karwoski, B.M. Prior, and R.B. Armstrong. Excitation failure in mouse soleus muscle injured by eccentric contractions. J. Physiol. (Lond.) 468: 487-499, 1993. Warren, G.L., D.A. Hayes, D.A. Lowe, B.M. Prior, and R.B. Armstrong. Materials fatigue initiates eccentric contraction-induced injury in rat soleus muscle. J. Physiol. (Lond.) 464: 477-489, 1993. Warren, G.L., D.A. Hayes, D.A. Lowe, and R.B. Armstrong. Mechanical factors in the initiation of eccentric contraction-induced injury in rat soleus muscle. J. Physiol. (Lond.) 464: 457-475, 1993. Warren, G.L., K.J. Cureton, W.F. Middendorf, C.A. Ray, and J.A. Warren. Red blood cell pulmonary capillary transit time during exercise in athletes. Med. Sci. Sports Exerc. 23: 1353-1361, 1991. Armstrong, R.B., G.L. Warren, and J.A. Warren. Mechanisms of exercise-induced muscle fiber injury. Sports Med. 12: 184-207, 1991. Cureton, K.J., and G.L. Warren. Criterion-reference standards for youth health-related fitness tests: a tutorial. Res. Q. Exerc. Sport 61: 7-19, 1990. Warren, G.L., K.J. Cureton, D.R. Dengel, R.E. Graham, and C.A. Ray. Is the gender difference in peak VO2 greater for arm than leg exercise? Eur. J. Appl. Physiol. 60: 149-154, 1990. Warren, G.L., K.J. Cureton, and P.B. Sparling. Does lung function limit performance in a 24-hour ultramarathon? Respir. Physiol. 78: 253-264, 1989. Warren, G.L., and K.J. Cureton. Modeling the effect of alterations in hemoglobin concentration on VO2max. Med. Sci. Sports Exerc. 21: 526-531, 1989. Journal Articles (submitted) Tsai, L.C., Y.A. Ko, K.E. Hammond, J.W. Xerogeanes, G.L.Warren, and C.M. Powers. Increasing hip and knee flexion during a drop landing task reduces tibiofemoral shear and compressive forces: implications for ACL injury prevention training. Submitted to Clin. Biomech. Nichenko, A.S., W.M. Southern, M. Atuan, J. Luan, K.B. Peissig, S.J. Folz, A.M. Beedle, G.L. Warren, and J.A. Call. Mitochondrial maintenance via autophagy contributes to functional skeletal muscle regeneration and remodeling. Submitted to Am. J. Physiol: Cell Physiol. Morelli, K.M., L.B. Brown, and G.L. Warren. NSAID impact on acute skeletal muscle injury: A systematic review and meta-analysis. Submitted to Br. J. Sports Med. Urso, M.L., C.T. Carrigan, C.A. Strohbach, A.S. Lin, R.E. Guldberg, and G.L. Warren. Matrix metalloprotease inhibition negatively affects signaling required for muscle regeneration following injury. Submitted to Eur. J. Appl. Physiol. Housley, S.N., D.L. Thompson, J.E. Lewis, and G.L. Warren. A proximal fibularis brevis muscle is associated with longitudinal split tendons: a cadaveric study. Submitted to J. Foot Ankle Surg. Dhere, R., K.R. Rogers, M.C. Maysilles, L. Tis, and G.L. Warren. Relative contributions of neural and muscular mechanisms to the repeated bout effect. Submitted to Eur. J. Appl Physiol. Book Chapters Millard-Stafford, M.L., T.K. Snow, and G.L. Warren. Chapter 7: Experimental design I – independent variables. ACSM’s Research Methods. Wolter Kluer, 2015, p. 121-142. Warren, G.L., and L.E. Palubinskas. Human and animal experimental muscle injury models. Skeletal Muscle Damage and Repair: Mechanisms and Interventions. Human Kinetics, 2008, p. 13-35. Warren, G.L. Acute and chronic contraction-induced muscle injury. Advances in Occupational Ergonomics and Safety. Amsterdam: IOS Press, 2001, p. 410-417. Armstrong, R.B., G.L. Warren, and D.A. Lowe. Mechanisms in the initiation of contraction-induced skeletal muscle injury. Repetitive Motion Disorders of the Upper Extremity. Rosemont, IL: American Academy of Orthopaedic Surgeons, 1995, p. 339-349. Armstrong, R.B., and G.L. Warren III. Strain-induced skeletal muscle fiber injury. Intermittent High Intensity Exercise: Preparation, Stresses and Damage Limitation. London: E & FN Spon, 1993, p. 275-285. U.S. Government Technical Reports Walker, T.B., U. Balldin, J. Fischer, W. Storm, and G. Warren. Effects of a commercial energy drink on acceleration tolerance and cognitive performance. AFRL-RH-BR-TR-2009-0063, released February 9, 2010. Scholarly Proceedings/Conference Abstracts Bonin, L., L. Mishaw, E. Teh, P. Chitika, and G.L. Warren. Effect of physical therapy on time to mobilization in traumatically-injured patients: A retrospective study. Submitted for presentation at the American Congress of Rehabilitation Medicine. Smelser, D.P., K.L. Robbins, P.M. Hopkins, G.L. Warren, and J.P. Irwin. Effectiveness of taping for reducing pain in patients with plantar fasciitis: A systematic review and meta-analysis. Proceedings of the Southeast Chapter of the American College of Sports Medicine, 43rd annual meeting, Greenville, SC, 2016. Lloyd, E., T. Ganas, J. Howe, P. Chitika, and G.L. Warren. Characteristics of traumatically-injured patients in the ICU that distinguish between those who receive an order for physical therapy and those who do not: A retrospective study. Proceedings of the Combined Sections Meeting of the American Physical Therapy Association, Anaheim, CA, 2016. Howe, J., E. Lloyd, T. Ganas, P. Chitika, and G.L. Warren. Characteristics of traumatically-injured patients in the ICU that are predictive of a patient receiving an order for physical therapy: A retrospective study. Proceedings of the fall meeting of the Physical Therapy Association of Georgia, Pine Mountain, GA, 2015. Ganas, T., E. Lloyd, J. Howe, P. Chitika, and G.L. Warren. Characteristics of traumatically-injured patients in the ICU that distinguish between those who receive an order for physical therapy and those who do not: A retrospective study. Proceedings of the 4th Annual Regenerative Rehabilitation Symposium, Rochester, MN, 2015. Le, G., D.A. Lowe, and G.L. Warren. Impact of estradiol on neutrophils and recovery of strength after traumatic muscle injury in ovariectomized female mice. Proceedings of the 4th Annual Regenerative Rehabilitation Symposium, Rochester, MN, 2015. Housley, S.N., J.E. Lewis, D.L. Thompson, and G.L. Warren. Proximal peroneus brevis muscle belly insertion and prevalence of longitudinal split tendon: a cadaveric study. Clin. Anat. 29(1): 87, 2015. doi: 10.1002/ca.22658. Tsai, L.C., V. Cheuy, G.L. Warren, K.E. Hammond, J.W. Xerogeanes, and C.M. Powers. Quadriceps and hamstring muscle morphology following anterior cruciate ligament reconstruction using an allograft. Proceedings of the annual meeting of the American College of Sports Medicine, San Diego, CA, 2015. Le, G., M.J. Jergenson, D.A. Lowe, and G.L. Warren. Estradiol enhances neutrophil infiltration into traumaticallyinjured skeletal muscle. FASEB J. 29: LB704, 2015. Li, M.T., L. Krishnan, N.J. Willett, G.L. Warren, and R.E. Guldberg. Microvascular constructs increase early vascularity in the limb but impede bone regeneration in a composite bone and muscle injury model. Proceedings of the Orthopaedic Research Society Annual Meeting, Las Vegas, NV, 2015. Guldberg, R., N. Willett, L. Krishnan, M. Li, J. Boerckel, B. Uhrig, and G. Warren. Preclinical models and regenerative strategies for composite limb trauma. Tissue Eng. Part A. 20: S43, 2014. Li, M.T., L. Krishnan, N. Servies, R.E. Guldberg, and G.L. Warren. Myoblast-seeded microvascular constructs facilitates healing of volumetric muscle loss in the biceps femoris. Proceedings of the 2014 Georgia Bio-Innovation Summit, Atlanta, GA, 2014. Tsai, R., A. Farquharson, J.D. Garcia, and G.L. Warren. Effect of balance training in individuals with ankle instability: a systematic review and meta-analysis. Proceedings of the annual meeting of the American College of Sports Medicine, Orlando, FL, 2014. Mader, T.L., A.G. Greising, D.A. Lowe, and G.L. Warren. Estrogen alters macrophage subpopulation and neutrophil responses following skeletal muscle injury. Proceedings of the annual meeting of the American College of Sports Medicine, Orlando, FL, 2014. Trost, J., M. Chen, T. Kimberly, D.A. Lowe, and G.L. Warren. Evaluating contraction-induced impairment in fiber excitability using magnetic stimulation in boys with DMD. Proceedings of the 2014 New Directions in Biology and Disease of Skeletal Muscle Conference, Chicago, IL, 2014. Li, M.T., L. Krishnan, N.J. Willett, T.J. Koob, R.E. Guldberg, and G.L. Warren. Amniotic membrane as a treatment strategy in a novel volumetric muscle loss model in the rat biceps femoris. Proceedings of the Orthopaedic Research Society Annual Meeting, New Orleans, LA, 2014. Mader, T.L., A.G. Greising, D.A. Lowe, and G.L. Warren. Estrogen alters macrophage subpopulation and neutrophil responses following skeletal muscle injury. Proceedings of the 3rd Annual Regenerative Rehabilitation Symposium, San Francisco, CA, 2014. Collins, B.C., T.L. Mader, C. Le, G.L. Warren, and D.A. Lowe. Estradiol alters the expression of key transcription factors that regulate skeletal muscle regeneration. Proceedings of the 2014 Advances in Skeletal Muscle Biology in Health & Disease meeting, Gainesville, FL, 2014 Mader, T.L., A.G. Greising, D.A. Lowe, and G.L. Warren. Estrogen alters macrophage and neutrophil recruitment and response following skeletal muscle injury. Proceedings of the 2014 Advances in Skeletal Muscle Biology in Health & Disease meeting, Gainesville, FL, 2014 Willett, N.J., M.A Li, B.A Uhrig, G.L. Warren, and R.E. Guldberg. Composite bone and muscle injury attenuates revascularization of a segmental bone defect. Proceedings of the 2013 North American meeting of the Tissue Engineering and Regenerative Medicine International Society, Atlanta, GA, 2013. Li, M.A., L. Krishnan, N.J. Willett, R.E. Guldberg, and G.L. Warren. Novel volumetric muscle loss model in the rat biceps femoris for screening of ECM-derived scaffolds. Proceedings of the 2013 North American meeting of the Tissue Engineering and Regenerative Medicine International Society, Atlanta, GA, 2013. Trost, J.P., M. Chen, G.L. Warren, D.A. Lowe, and T.J. Kimberley. Wrist extensor muscle strength and fatigue assessed by peripheral and transcranial magnetic stimulation. Proceedings of the University of Minnesota Clinical and Translational Science Institute 2013 Poster Session, Minneapolis, MN, 2013. Trost, J.P., M. Chen, T.J. Kimberley, G.L. Warren, and D.A. Lowe. Wrist extensor muscle strength and fatigue assessed by peripheral and transcranial magnetic stimulation. Proceedings of the 2013 Marzolf Muscular Dystrophy Symposium, Minneapolis, MN, 2013. Morton, R., J. Mogill, T. McLeod, B. Buchanan, M. Theobald, K.M., J. Garcia, and G.L. Warren. Comparison of magnetic stimulation to electrical stimulation in activating the knee extensors. Proceedings of the fall meeting of the Physical Therapy Association of Georgia, Atlanta, GA, 2013. Stewart, L.M., G.L. Warren, A.J. Butler, and L. Rogers. A systematic review and meta-analysis of the impact on urinary incontinence symptoms when abdominal muscles are trained concurrently with pelvic floor muscles. Proceedings of the annual meeting of the South Carolina Chapter of the American Physical Therapy Association, Myrtle Beach, SC, 2013. Miller, J., L. Despres, A. Farthing, A Garrido, J. Garcia, K. Morelli, J. Lewis, J. Donnelly, and G.L. Warren. Clinical predictors of the ability to activate the knee extensors. Proceedings of the Combined Sections Meeting of the American Physical Therapy Association, San Diego, CA, 2013. Li, M.A., N.J. Willett, B.A Uhrig, J.D. Boerckel, G.L. Warren, and R.E. Guldberg. Concomitant volumetric muscle loss delays revascularization in the healing of a segmental bone defect. Proceedings of the Orthopaedic Research Society Annual Meeting, San Antonio, TX, 2013. Willett, N.J., M.A Li, B.A Uhrig, G.L. Warren, and R.E. Guldberg. Composite bone and muscle injury attenuates rhBMP-2 mediated tissue regeneration, limb function, and vascular supply. Proceedings of the Biomedical Engineering Society Annual Meeting, Atlanta, GA, 2012. Jones, W., T. Robertson, M. Newton-West, C. Yurko, N.J. Willett, A. Li, G.L. Warren, and R.E. Guldberg. Magnetic resonance imaging assessment of inflammation in traumatically-injured rat quadriceps muscle. Proceedings of the 2nd Annual Regenerative Rehabilitation Symposium, Pittsburgh, PA, 2012. Brown, L.B., B. Adler, K.M. Morelli, and G.L. Warren. Effect of NSAID use on muscle injury: a systematic review and meta-analysis. Proceedings of the 2nd Annual Regenerative Rehabilitation Symposium, Pittsburgh, PA, 2012. Novotny, S.A., G.L. Evans, D.J. Nuckley, G.L. Warren, and D.A. Lowe. Low-amplitude, high-frequency vibration and musculoskeletal health in the mdx mouse model of Duchenne muscular dystrophy. Proceedings of the American Society of Bone and Mineral Research, Minneapolis, MN, 2012 Willett, N.J., M.A Li, B.A Uhrig, T. Lundgren, J.D. Boerckel, G.L. Warren, and R.E. Guldberg. Attenuated BMP-2 mediated tissue regeneration in a rat model of composite bone and muscle injury. Proceedings of Tissue Engineering and Regenerative Medicine International Society World Congress, Vienna, Austria, 2012 Willett, N.J., M.A Li, B.A Uhrig, T. Lundgren, J.D. Boerckel, G.L. Warren, and R.E. Guldberg. Concomitant volumetric muscle loss impairs an early vascular response in a composite bone-muscle defect model. Proceedings of the American Society of Bone and Mineral Research Topical Meeting: Bone and Skeletal Muscle Interactions, Kansas City, MO, 2012. Novotny, S.A., D.J. Nuckley, G.L. Warren, and D.A. Lowe. Low-amplitude, high-frequency vibration and musculoskeletal health in the mdx mouse model of Duchenne muscular dystrophy. Proceedings the American Society of Bone and Mineral Research Topical Meeting: Bone and Skeletal Muscle Interactions, Kansas City, MO, 2012. Adler, B., L.B. Brown, K.M. Morelli, and G.L. Warren. Effect of NSAID use on muscle injury: a systematic review and meta-analysis. Med. Sci. Sports Exerc. 44:S566, 2012. Warren, G.L., A.K. Farthing, B.B. Piaro, S.R. Coley, C.W. Satterfield, C.D. Vlahos, and J.E. Lewis. Does a secondary loss of strength occur following induction of muscle injury? Med. Sci. Sports Exerc. 44:S566, 2012. Alexander, R., M. Anderson, J. Freeman, D. Hallahan, and G. Warren. A novel procedure for determining knee extensor muscle activation during cycling. Proceedings of the annual meeting of the South Carolina Chapter of the American Physical Therapy Association, Greenville, SC, 2012. Holbrook, J., K. Williams, B. Mann, L. Brown, J. Miller, L. Despres, A. Farthing, A. Garrido, G. Warren, J. Garcia, K. Morelli, J. Lewis, and J. Donnelly. Clinical predictors of muscle activation of the knee extensors during MVIC. Proceedings of the annual meeting of the South Carolina Chapter of the American Physical Therapy Association, Greenville, SC, 2012. Capps, K., B. Espy, C. Hiers, and G. Warren. Is hospital length of stay different between unilateral and bilateral arthroplasty in the lower extremity? A systematic review and meta-analysis. Proceedings of the annual meeting of the South Carolina Chapter of the American Physical Therapy Association, Greenville, SC, 2012. Brown, S., E. Dashiell, P. King and G. Warren. The restorative effects of MIRE (monochromatic near-infrared energy) therapy on lower extremity sensation in patients with diagnosed peripheral neuropathy: a systematic review and meta-analysis. Proceedings of the annual meeting of the South Carolina Chapter of the American Physical Therapy Association, Greenville, SC, 2012. Urso, M.L., C.A. Strohbach, H.L. Eustis, and G.L. Warren. Matrix metalloprotease inhibitor Batimastat does not improve skeletal muscle function post-traumatic injury, but does modulate the MMP response. FASEB J. 26:1086.2, 2012. Li, M.A., N.J. Willett, B.A. Uhrig, G.L. Warren, and R.E. Guldberg. Muscle injury causes delayed revascularization of bone in a composite injury mode. Proceedings of the 16th Annual Hilton Head “Regenerative Medicine: Innovations for Clinical Applications” Workshop, Hilton Head, SC, 2012. Farthing, A.K., S.R. Coley, B.B. Piaro, C.W. Satterfield, C.D. Vlahos, J.E. Lewis, and G.L. Warren. Does a secondary loss of strength occur following induction of muscle injury? Proceedings of the Southeast Chapter of the American College of Sports Medicine, 39th annual meeting, Jacksonville, FL, 2012. Li, M.A, N.J. Willett, T. Lundgren, B.A Uhrig, R.E. Guldberg, and G.L. Warren. Functional analysis of limb recovery with autograft treatment following volumetric muscle loss in the quadriceps femoris. Proceedings of the Orthopaedic Research Society Annual Meeting, San Francisco, CA, 2012. Willett, N.J., M.A Li, B.A Uhrig, J.D. Boerckel, G.L. Warren, and R.E. Guldberg. Muscle injury attenuates BMP-2 mediated bone regeneration in a rat model of composite bone and muscle injury. Proceedings of the Orthopaedic Research Society Annual Meeting, San Francisco, CA, 2012. Anderson, B., E. Trent, M. Newton-West, C. Yurko, G.L. Warren, A. Li, N.J. Willett, and R.E. Guldberg. MRI assessment of inflammation in traumatically-injured rat muscle. Proceedings of the 3rd Annual Workshop for Magnetic Resonance at Georgia Tech, Atlanta, GA 2011. Li, M.A, N.J. Willett, T. Lundgren, B.A Uhrig, R.E. Guldberg, and G.L. Warren. Quantitative characterization of a novel volumetric muscle loss model in the rat. Proceedings of the 2011 North American meeting of the Tissue Engineering and Regenerative Medicine International Society, Houston, TX, 2011. Willett, N.J., M.A Li, B.A Uhrig, J.D. Boerckel, G.L. Warren, and R.E. Guldberg. Muscle injury attenuates BMP-2 mediated bone regeneration in a rat model of composite tissue injury. Proceedings of the 2011 North American meeting of the Tissue Engineering and Regenerative Medicine International Society, Houston, TX, 2011. Uhrig, B.A., N.J. Willett, M.A. Li, J.D. Boerckel, G.L. Warren, and R.E. Guldberg. Preclinical models of composite tissue limb trauma. Proceedings of the 2011 Georgia Tech Institute of Bioscience and Bioengineering Industrial Partners Symposium, Atlanta, GA, 2011. Farmer, A., D. Allcott, G. Schmaltz, S. Alexander, M. Anderson, B. Anderson, and G.L Warren. The effect of body position in the sagittal plane on electrically-stimulated strength of the knee extensors. Proceedings of the fall meeting of the Physical Therapy Association of Georgia, Dahlonega, GA, 2011. Coley, S.R., A.K. Farthing, B.B. Piaro, C.W. Satterfield, C.D. Vlahos, J.E. Lewis, and G.L. Warren. Does a secondary loss of strength occur following induction of muscle injury? Proceedings of the fall meeting of the Physical Therapy Association of Georgia, Dahlonega, GA, 2011. Fuller, N., C. Hobby, J.B. Williams, and G.L. Warren. Effects of proprioceptive neuromuscular facilitation on athletic performance: a systematic review and meta-analysis. Proceedings of the fall meeting of the Physical Therapy Association of Georgia, Dahlonega, GA, 2011. Pope, S., D. Tyler, Y. Chen, and G.L. Warren. Efficacy of constraint-induced movement therapy (CIMT) on the pediatric population with cerebral palsy: a systematic review and meta-analysis. Proceedings of the fall meeting of the Physical Therapy Association of Georgia, Dahlonega, GA, 2011. Cornell, B., M. Jackson, R. Canecchio, and G.L. Warren. Effect of thoracic manipulation on neck pain and function: a meta-analysis. Proceedings of the fall meeting of the Physical Therapy Association of Georgia, Dahlonega, GA, 2011. Dukes, R.E., J.M. Kalmbach, R.R. Warren, G.L. Warren, Y.T. Wang, and J.E. Lewis. A comparison of barefoot running versus shod running on peak impact force and ankle excursion: a systematic review and meta-analysis. Proceedings of the fall meeting of the Physical Therapy Association of Georgia, Dahlonega, GA, 2011. Sawyer, A., S. Martinez, and G.L. Warren. Impact of yoga on low back pain and function: a systematic review and meta-analysis. Proceedings of the fall meeting of the Physical Therapy Association of Georgia, Dahlonega, GA, 2011. Morrison, S., S. Holness, C. Stinson, and G.L. Warren. Open kinetic chain vs. closed kinetic chain exercise in the treatment of patients with ACL injuries: a meta-analysis. Proceedings of the fall meeting of the Physical Therapy Association of Georgia, Dahlonega, GA, 2011. Willett, N.J., M.A. Li, B.A. Uhrig, G.L. Warren, and R.E. Guldberg. Muscle injury attenuates BMP-2 mediated tissue regeneration in a novel rat model of composite bone and muscle injury. Proceedings of the ASME 2011 Summer Bioengineering Conference, Farmington, PA, 2011. Willett, N.J., M.A. Li, B.A. Uhrig, B. Boyan, G.L. Warren, and R.E. Guldberg. Tissue regeneration in a novel rat model of composite bone and muscle injury. Proceedings of the Pediatric Technology and Surgery Research Forum, Atlanta, GA, 2011. Warren, G.L., S.A. Novotny, S.M. Greising, and D.A. Lowe. Estrogen modulation of inflammatory gene expression following traumatic muscle injury. Med. Sci. Sports Exerc. 43:S253, 2011. Call, J.A., M. D. Eckhoff, K.A. Baltgalvis, G.L. Warren, and D.A. Lowe. Dystrophin is not required for skeletal muscle to adapt to repeated bouts of lengthening contractions. FASEB J. 25:1105.13, 2011. Willett, N.J., M.A. Li, B.A. Uhrig, B. Boyan, G.L. Warren, and R.E. Guldberg. Functional and structural analysis of tissue regeneration using a novel rat model of composite bone and muscle injury. Proceedings of the 15th Annual Hilton Head “Regenerative Medicine: Innovations for Clinical Applications” Workshop, Hilton Head, SC, 2011. Li, M.A., N.J. Willett, B.A. Uhrig, G.L. Warren, and R.E. Guldberg. Quantitative analysis of limb recovery in a novel rat model with severe skeletal muscle defect. Proceedings of the 15th Annual Hilton Head “Regenerative Medicine: Innovations for Clinical Applications” Workshop, Hilton Head, SC, 2011. Li, M.A., N.J. Willett, B.A. Uhrig, G.L. Warren, and R.E. Guldberg. Functional and structural analysis of limb restoration using a novel rat model of composite bone and muscle injury. Proceedings of the Georgia Tech Research & Innovation Conference, Atlanta, GA, 2011. Willett, N.J., M.A. Li, B.A. Uhrig, G.L. Warren, and R.E. Guldberg. Functional and structural analysis of limb restoration using a novel rat model of composite bone and muscle injury. Proceedings of the Orthopaedic Research Society Annual Meeting, Long Beach, CA, 2011. Novotny, S.A., D.J. Nuckley, P.A. Petit, K.A. Baltgalvis, G.L. Warren, and D.A. Lowe. Bone strength and geometry are compromised in a mouse model of Duchenne muscular dystrophy: Can vibration prevent or reverse this response. J. Bone Miner. Res. 25(Suppl 1):S225, 2010. Kressler, J., M. Millard-Stafford, and G.L. Warren. Quercetin improves aerobic capacity and endurance performance: a meta-analysis. Proceedings of the American Physiological Society and the American College of Sports Medicine “Integrative Biology of Exercise” joint meeting, Miami, FL, 2010. Zhao, Z., S.M. Fridenmaker, and G.L. Warren. Modest enhancement of knee extensor MVC strength and EMG activity when the body is tilted backwards. Med. Sci. Sports Exerc. 42:S410, 2010. Conger, S.A., G.L. Warren, and M.L. Millard-Stafford. Addition of caffeine to carbohydrate: improved ergogenic effect for endurance exercise? Med. Sci. Sports Exerc. 42:S79, 2010. Szelenyi, E.R., G.L. Warren, and M.L Urso. Innate resolution of traumatic injury-induced skeletal muscle inflammation is initiated within 24 hours and involves MKP-1 induction, Hsf-1 disinhibition, and Hsp27 expression. FASEB J. 24:753.9, 2010. Zhao, Z.W., S.M. Fridenmaker, and G.L. Warren. Effects of body position on muscle strength, percent muscle activation, and EMG activity of the knee extensors. Proceedings of the Southeast Chapter of the American College of Sports Medicine, 37th annual meeting, Greenville, SC, 2010. Michael, D.M., M. Hardy, J. Balmes, L. Bankston, K. Benton, L. Carmichael, L. Huey, A. Nebedum, C. O’Dell, and G.L. Warren. The use of virtual reality gaming as a tool for improving fitness. Proceedings of the Southeast Chapter of the American College of Sports Medicine, 37th annual meeting, Greenville, SC, 2010. Novotny, S.A., K.A. Baltgalvis, G.L. Warren, and D.A. Lowe. Functional relationship of bone to muscle is altered in dystrophic mice. Proceedings of the 2009 Marzolf Muscular Dystrophy Symposium, Minneapolis, MN, 2009. Warren, G.L., T. Hulderman, A.L. Liston, and P.P. Simeonova. Altered Wnt signaling after skeletal muscle injury in CCR2-deficient mice. Appl. Physiol. Nutr. Metab. 34:1163, 2009. Burton, N.B., M.A. Hardy, R.H. Glaser, A.H. Honeycutt, M.B. Hubier, C.M. Ready, and G.L. Warren. Effects of caffeinated and uncaffeinated energy drinks on muscular strength and endurance. Med. Sci. Sports Exerc. 41:S320, 2009. Barnes, B.R., E.R. Szelenyi, G.L. Warren, and M.L. Urso. Traumatic skeletal muscle injury results in dual regulation of myostatin through binding protein and diminished expression. Med. Sci. Sports Exerc. 41:S24, 2009. Urso, M.L., E.R. Szelenyi, G.L. Warren, and B.R. Barnes. Traumatic skeletal muscle injury alters post-translational matrix metalloprotease-3 expression. Med. Sci. Sports Exerc. 41:S456, 2009. Burton, N.B., R.H. Glaser, M.A. Hardy, A.H. Honeycutt, M.B. Hubier, C.M. Ready, and G.L. Warren. Effects of a caffeinated energy drink on muscular strength and endurance. Proceedings of the Southeast Chapter of the American College of Sports Medicine, 36th annual meeting, Birmingham, AL, 2009. Conger, S.A., G.L. Warren, and M.L. Millard-Stafford. Caffeine co-ingested with carbohydrate: additional ergogenic effect for endurance exercise? Proceedings of the Southeast Chapter of the American College of Sports Medicine, 36th annual meeting, Birmingham, AL, 2009. Warren, G.L., T. Hulderman, A.L. Liston, and P.P. Simeonova. Differential growth factor expression in traumatically-injured muscle from C57BL/6 and CCR2-/- mice. Proceedings of the 2008 North American meeting of the Tissue Engineering and Regenerative Medicine International Society, San Diego, CA, 2008. Maresca, R.D., N.D. Park, K.I. McKibans, and G.L. Warren. Caffeine improves maximal voluntary strength and activation in uninjured but not injured muscle. Proceedings of the fall meeting of the Physical Therapy Association of Georgia, Dahlonega, GA, 2008. McKibans, K., R. Maresca, N. Park, and G.L. Warren. Effect of caffeine on muscular performance: a meta-analysis. Proceedings of the spring meeting of the Physical Therapy Association of Georgia, Savannah, GA, 2008. Park, N., R. Maresca, K. McKibans, and G.L. Warren. Does caffeine ingestion attenuate the strength loss following the performance of injurious eccentric contractions? Proceedings of the Southeast Chapter of the American College of Sports Medicine, 35th annual meeting, Birmingham, AL, 2008. Lowe, D.A., S.M. Greising, A.L. Moran, E. Song, and G.L. Warren. Soleus muscle from aged, ovarian-failed and adult, ovariectomized mice respond differently to estradiol treatment. Proceedings of the Shock Center Aging Conference, San Antonio, TX, 2007. Michael, D.M. and G.L. Warren. Effect of trigger point treatment on muscle activation patterns in hip extension movement. J. Musculoskeletal Pain. 15(S13):32, 2007. Trilk, J.L., M.L. Millard-Stafford, K.J. Cureton, J.E. Wingo, G.L. Warren, and M Buyckx. Hydration during exercise in warm, humid conditions: effect of a caffeinated sports drink. Med. Sci. Sports Exerc. 39:S100-101, 2007. Allen, T., J. Hill, L. Jones, R. Maresca, K. McKibans, R. Morgan, N. Park, T. Wanko, and G.L. Warren. Does caffeine ingestion attenuate the strength loss following the performance of injurious eccentric contractions? Proceedings of the spring meeting of the Physical Therapy Association of Georgia, Augusta, GA, 2007. Millard-Stafford, M.L., K.J. Cureton, J.E. Wingo, J. Trilk, and G.L. Warren. Caffeine co-ingested with carbohydrate: ergogenic effects without altered metabolism during exercise in the heat. Proceedings of the American College of Sports Medicine Conference on Integrative Physiology of Exercise, Indianapolis, IN, 2006. Moran, A.L., G.L. Warren, and D.A. Lowe. Estradiol replacement or wheel running reverses skeletal muscle contractile dysfunction in mature ovariectomized mice. Med. Sci. Sports Exerc. 38:S374, 2006. Millard-Stafford, M., G.L. Warren, K.M. Hitchcock, A. Singhal, T.K. Snow, and J.E. Parsons. Added protein to carbohydrate: no acute performance benefit but facilitates subsequent endurance capacity. Med. Sci. Sports Exerc. 38:S113, 2006. Maranzanno, M, J. Metz, M. Wadopian, and G. Warren. Ergogenic effects of caffeine in endurance exercise: peripherally- or centrally-mediated? Proceedings of the spring meeting of the Physical Therapy Association of Georgia, Savannah, GA, 2006. Hitchcock, K.M, G.L. Warren, M. Millard-Stafford, and T.K. Snow. Plasma IL-6 level is not attenuated with carbohydrate ingestion during exercise in the heat. Proceedings of the Southeast Chapter of the American College of Sports Medicine, 34th annual meeting, Charlotte, NC, 2006. Albert, A., J. Campbell, K. Cumuze, N. Fernandez, M. Nilson, A. Winston, and G. Warren. Leg length discrepancy: comparison of techniques and prevalence in an apparently healthy population. Proceedings of the fall meeting of the Physical Therapy Association of Georgia, Dahlonega, GA, 2005. Moran, A.L., G.L. Warren, and D.A. Lowe. Ovarian hormone removal and estradiol replacement: effects on skeletal muscle strength and myosin structure. Proceedings of the Women's Health Research Conference 2005, Minneapolis, MN, 2005. Millard-Stafford, M., G.L. Warren, K.M. Hitchcock, R. I. Welling, L.B. Rosskopf, and T.K. Snow. Fluid replacement in the heat: effects of betaine. Med. Sci. Sports Exerc. 37:S28, 2005. Moran, A.L., G.L. Warren, and D.A. Lowe. The effects of age on passive and active stiffness of fast- and slow-twitch skeletal muscle. The Physiologist, 47:318, 2004. Warren, G.L., K. Rogers, K. Billings, L. O’Farrell, S. Sayers, and P. Clarkson. CK-MM autoantibodies after skeletal muscle injury. Med. Sci. Sports Exerc. 36:S289, 2004. Simeonova, P.P., G.L. Warren, W. Kuziel, D. Mishra, and T. Hulderman. Skeletal muscle regeneration and chemokines. Proceedings of the 2003 FASEB Summer Research Conference “Skeletal Muscle Satellite and Stem Cells”, Tucson, AZ, 2003. McKinstry, M., K. Brumbaugh, T. Hulderman, G.L. Warren, M. Summan, M.I. Luster and P. Simeonova. Transcriptional profiling of TNF-α-induced effects on skeletal myogenic differentiation. FASEB J. 17:A1067, 2003. Summan, M., T. Hulderman, M. McKinstry, G.L. Warren, and P.P. Simeonova. Early markers of skeletal muscle injury revealed by cDNA array. FASEB J. 17:A1365, 2003. Wenke, J.C., G.L. Warren, C.R. Rathbone, and R.B. Armstrong. High force contractions as a countermeasure to muscle atrophy. FASEB J. 17:A957, 2003. Warren, G.L., L. O'Farrell, M.C. Maysilles, K.R. Rogers, and P.P. Simeonova. Velocity-dependent recovery of strength after traumatic muscle injury: no effect of IL-6 deficiency. Med. Sci. Sports Exerc. 35:S238, 2003. Rathbone, C.R., J.C. Wenke, G.L. Warren, and R.B. Armstrong. Importance of satellite cells in recovery from eccentric contraction-induced injury. Med. Sci. Sports Exerc. 35:S157, 2003. Crute, J., K. Green, R. Maher, B. Taylor, A. Tudor, T. Yudis, and G. Warren. Plantar pressure and muscle activation patterns during treadmill walking in able-bodied men. Proceedings of the annual meeting of the Physical Therapy Association of Georgia, Kennesaw, GA, 2002. Lowe, D.A., G.L. Warren, L.A. Snow, D.D. Thomas, and L.V. Thompson. The effects of age and muscle activity on muscle protein structure and function. Proceedings of the Gerontological Society of America Convention 2002, Boston, MA, 2002. Slade, J.M., C.S. Bickel, G.L. Warren, and G.A. Dudley. Variable frequency train electrical stimulation of the quadriceps femoris in complete spinal cord injured individuals. Med. Sci. Sports Exerc. 34:S262, 2002. Lowe, D.A., G.L. Warren, L.A. Snow, D.D. Thomas, and L.V. Thompson. Does myosin structure and function change with increased or decreased muscle activity? Med. Sci. Sports Exerc. 34:S186, 2002. Bickel, C.S., J.M. Slade, G.L. Warren, and G.A. Dudley. Muscular fatigue in two different human skeletal muscles with force augmentation using variable frequency train stimulation. Med. Sci. Sports Exerc. 34:S261, 2002. Lowe, D.A., G.L. Warren, L.M. Snow, D.D. Thomas, and L.V. Thompson. Reversibility of age-related changes in myosin structure and function in muscle. Proceedings of the 15th Annual AFAR Grantee Conference, New York, NY, 2002. Long, A., J. Williams, M. Heringer, K. Bishop, K. Broadway, C. Newton, S. Bickel, G. Warren, and G. Dudley. Temporal patterns of EMG and plantar pressures in SCI subjects during body weight-supported treadmill walking. Proceedings of the annual meeting of the Physical Therapy Association of Georgia, Kennesaw, GA, 2001. Slade, J., C.S. Bickel, M. Floersheim, L. VanHiel, G.L. Warren, and G.A. Dudley. Optimizing surface electrical stimulation for rehabilitation of skeletal muscle. Shepherd Center Research Day, Atlanta, GA, 2001. Warren, G.L. Acute and chronic contraction-induced muscle injury. Proceedings of the International Society for Occupational Ergonomics and Safety, 15th annual meeting, Fairfax, VA, 2001. Heringer, M., K. Bishop, K. Broadway, A. Long, C. Newton, J. Williams, S. Bickel, G. Warren, and G. Dudley. Temporal patterns of EMG and plantar pressures in SCI subjects during body weight-supported treadmill walking. Proceedings of the XXIIIrd International Symposium of the Center for Research in Neurological Sciences of Université de Montréal, Montreal, Canada, 2001. Kegley, K.M., S. Matteson, G.L. Warren, and G.K. Pavlath. Reduced primary myofiber number in NFAT4 knockout mice leads to decreased muscle size in the adult. Proceedings of the Society for Developmental Biology conference on “The Muscle Biology of Muscle Development and Disease”, Monterey, CA, 2000. Kegley, K.M., S. Matteson, G.L. Warren, and G.K. Pavlath. NF-AT4 influences development and/or survival of Type II skeletal muscle fibers. J. Aging Phys. Activity 8:292, 2000. Warren, G.L., G.K. Pavlath, and C.P. Ingalls. Less MyoD and myogenin expression following contraction-induced muscle injury compared to traumatic injury. J. Aging Phys. Activity 8:277, 2000. Nofal, T.S., and G.L. Warren. Effect of exercise-induced muscle injury on plantar pressures during treadmill walking. Med. Sci. Sports Exerc. 32:S73, 2000. Saunders, M.J., E.M. Evans, S.A. Arngrimsson, J.D. Allison, G.L. Warren, and K.J. Cureton. Relation between muscle activation and the slow component rise in oxygen uptake during cycling. Proceedings of the Southeast Chapter of the American College of Sports Medicine, 28th annual meeting, Charlotte, NC, 2000. Fennessey, J.M., G.L. Warren, and M.L. Millard-Stafford. The effects of a creatine-supplemented diet on muscle injury in mice. Proceedings of the Southeast American College of Sports Medicine, 28th annual meeting, Charlotte, NC, 2000. Nofal, T.S., and G.L. Warren. Effects of speed and grade on plantar pressure measurements during treadmill walking. Proceedings of the Southeast Chapter of the American College of Sports Medicine, 28th annual meeting, Charlotte, NC, 2000. Allen, M.R., C.P. Ingalls, G.L. Warren, and S.A. Bloomfield. Time course of bone and muscle alterations after hindlimb suspension and 24-hour reambulation in mice. J. Bone Min. Res. 14(Suppl. 1):F018, 1999. Wenke, J.C., G.L. Warren, C.P. Ingalls, and R.B. Armstrong. Does treadmill training slow the recovery of eccentric contraction-induced injury? Med. Sci. Sports Exerc. 31:S73, 1999. Ingalls, C.P., G.L. Warren, S.L. Hamilton, and R.B. Armstrong. Dihydropyridine and ryanodine receptor binding after eccentric contractions in mouse skeletal muscle. Med. Sci. Sports Exerc. 31:S72, 1999. Warren, G.L., C.P. Ingalls, and R.B. Armstrong. Altered calcium homeostasis in mouse soleus muscles after hindlimb suspension and reloading. Med. Sci. Sports Exerc. 31:S221, 1999. Ingalls, C.P., G.L. Warren, and R.B. Armstrong. Torque-EMG relationship in mouse muscle after in vivo eccentric or concentric contractions. Med. Sci. Sports Exerc. 30:S102, 1998. Warren, G.L., C.P. Ingalls, and R.B. Armstrong. Marked effect of temperature on the eccentric contraction-induced force deficit. Med. Sci. Sports Exerc. 30:S102, 1998. Warren, G.L., D.A. Lowe, C.P. Ingalls, and R.B. Armstrong. Eicosanoid release by mouse EDL muscle after 150 in vivo eccentric contractions. Med. Sci. Sports Exerc. 29:S53, 1997. Ingalls, C.P., G.L. Warren, and R.B. Armstrong. Excitation contraction coupling failure in mouse EDL muscle after eccentric contractions in vivo. Med. Sci. Sports Exerc. 29:S272, 1997. Warren, G.L., H.A. Hogan, J.A. Groves, R.B. Armstrong, and S.A. Bloomfield. The effect of training on tibial bone properties in estrogen-deficient mice. Proceedings of the Society for Physical Regulation in Biology and Medicine, 16th annual meeting, Chicago, IL, p. 7, 1996. Hermann, K.M., G.L. Warren, M.R. Masselli, and R.B. Armstrong. Muscle recruitment variation between two bouts of eccentric exercise. The Physiologist 39:A-57, 1996. Ingalls, C.P., G.L. Warren, and R.B. Armstrong. Dissociation of MHC and actin contents from force production in muscles injured by eccentric contractions. The Physiologist 39:A-12, 1996. Warren, G.L., J.H. Williams, C.W. Ward, H. Matoba, C.P. Ingalls, K.M. Hermann, and R.B. Armstrong. Decreased contraction economy in mouse EDL muscle injured by eccentric contractions. The Physiologist 39:A-55, 1996. White-Welkley, J.E., J.A. Eiser, G.L. Warren, A. Cohen, J. Mulchahey, K.V., Thrivikraman, P.M. Plotsky, and D.B. Neill. Effects of treadmill training on plasma ACTH and brain CRF responses to heterotypic stress. Med. Sci. Sports Exerc. 28:S109, 1996. Bloomfield, S.A., G.L. Warren, C.L. Inman, and R.B. Armstrong. Early enzyme changes in murine tibiae after highforce muscle contractions. J. Bone Min. Res. 10:S409, 1995. Boorstein, D.B., C.P. Ingalls, G.L. Warren, D.A. Lowe, and R.B. Armstrong. Mitochondrial coupling state in the mouse EDL muscle following eccentric exercise. Med. Sci. Sports Exerc. 27:S37, 1995. Lowe, D.A., G.L. Warren, C.P. Ingalls, D.B. Boorstein and R.B. Armstrong. Protein metabolism in mouse EDL muscle 0-336 hrs after eccentric contraction-induced injury. Med. Sci. Sports Exerc. 27:S37, 1995. Ingalls, C.P., G.L. Warren, D.A. Lowe, D.B. Boorstein, and R.B. Armstrong. Anesthetic effects on the contractile function of mouse ankle dorsiflexor muscles in vivo. Med. Sci. Sports Exerc. 27:S217, 1995. Warren, G.L., D.A. Lowe, C. Inman, O.M. Orr, H.A. Hogan, S.A. Bloomfield, and R.B. Armstrong. Estradiol effect on anterior crural muscle:tibial bone relationship and susceptibility to injury. Med. Sci. Sports Exerc. 27:S159, 1995. Higbie, E.J., K.J. Cureton, and G.L. Warren. Effects of concentric and eccentric isokinetic training on muscle strength, cross-sectional area and neural activation. Med. Sci. Sports Exerc. 26:S31, 1994. Lowe, D.A., G.L. Warren, and R.B. Armstrong. Protein degradation in mouse soleus and EDL muscle following eccentric contraction-induced injury. Med. Sci. Sports Exerc. 26:S123, 1994. Warren, G.L., D.A. Lowe, D.A. Hayes, M.A. Farmer, and R.B. Armstrong. Cell membrane damage in exerciseinduced muscle fiber injury. Med. Sci. Sports Exerc. 26:S124, 1994. White, J.E., R.K. Dishman, B.N. Bunnell, G.L. Warren, E.H. Mougey, and J.L. Meyerhof. Chronic treadmill training moderates ACTH responses to homotypic and heterotypic stress. Med. Sci. Sports Exerc. 25:S91, 1993. Lowe, D., G. Warren, D. Hayes, B. Prior, and R. Armstrong. Running downhill does not injure mouse soleus muscles. Int. J. Sports Med. 14:104-105, 1993. Lowe, D., J. Desmond, G. Warren, D. Hayes, B. Prior, and R. Armstrong. Extracellular [Ca2+] does not affect eccentric contraction-induced injury. FASEB J. 7:A806, 1993. Prior, B., G. Warren, D. Hayes, D. Lowe, J. Desmond, and R. Armstrong. Positive work done by continued crossbridge cycling and the elastic components in inactively shortened muscle. FASEB J. 7:A224, 1993. Warren, G., D. Hayes, D. Lowe, B. Prior, J. Desmond, and R. Armstrong. Greater eccentric contraction-induced injury occurs in fast muscle. FASEB J. 7:A806, 1993. Warren, G., D. Lowe, D. Hayes, B. Prior, C. Karwoski, and R. Armstrong. Excitation-contraction coupling loss in eccentric contraction-induced muscle injury. The Physiologist 35:201, 1992. Lowe, D., G. Warren, D. Hayes, B. Prior, and R. Armstrong. Exercise-induced muscle injury: materials fatigue. Med. Sci. Sports Exerc. 24:S142, 1992. Prior, B., G. Warren, D. Hayes, D. Lowe, and R. Armstrong. Mechanical factors in the storage of muscle elastic energy. Med. Sci. Sports Exerc. 24:S116, 1992. Warren, G., D. Hayes, D. Lowe, W. Guo, and R.B. Armstrong. Mechanical factors in exercise-induced muscle injury. FASEB J. 5:A1036, 1991. Warren, G.L., K.J. Cureton, W.F. Middendorf, C.A. Ray, and J.A. Warren. Role of diffusion limitation in exerciseinduced hypoxemia. Med. Sci. Sports Exerc. 22:S98, 1990. Cureton, K., G. Warren, W. Middendorf, C. Ray, and J. Warren. Lung diffusing capacity in highly-trained endurance athletes. Int. J. Sports Med. 11:405, 1990. Middendorf, W., G. Warren, K. Cureton, C. Ray, and J. Warren. Incidence of exercise-induced hypoxemia in male and female athletes. Int. J. Sports Med. 11:404, 1990. Warren, G., K. Cureton, W. Middendorf, C. Ray, and J. Warren. Validity and reliability of pulse oximetry in highly trained endurance athletes. Int. J. Sports Med. 11:405, 1990. Cureton, K.J., G. Warren, J. Gilliam, D. Dengel, R. Graham, and C. Ray. Ratings of perceived exertion, hyperventilation, and blood lactate during arm and leg exercise. Med. Sci. Sports Exerc. 21:S5, 1989. Warren, G.L., K.J. Cureton, and W.F. Middendorf. Pulmonary capillary red blood cell transit time during exercise in highly-trained cyclists. The Physiologist 32:163, 1989. Warren, G.L., K.J. Cureton, and P.B. Sparling. Does lung function limit performance in a 24-hour ultramarathon? Proceedings of the First International Olympic Committee World Congress on Sport Science, Colorado Springs, CO, 1989. Warren, G., K. Cureton, J. Wyllie, D. Dengel, R. Graham, and C. Ray. Is the sex difference in peak VO2 greater for arm exercise than for leg exercise? Med. Sci. Sports Exerc. 20:S18, 1988. Warren, G.L. Modeling the effects of induced anemia and erythrocythemia on VO2max. Proceedings of the Southeast Chapter of the American College of Sports Medicine, Winston-Salem, NC, 1988. Grants and Funding: External (research; funded proposals) “Combining Clinically Available Rehabilitative and Regenerative Strategies to Improve Functional Outcomes after Severe Extremity Trauma” DOD grant in collaboration with the U.S. Army Institute of Surgical Research, 2015-2018, Co-PI, $1,418,490 (GSU portion: $225,001). “Interaction of Estrogen, Age and Activity on Musculoskeletal Strength in Females” NIH R01 grant (competitive renewal) in collaboration with the University in Minnesota, 2014-2019, Co-PI, $2,232,525 (GSU portion: $434,676). “Engraftment Strategies for Functional Repair of Composite Musculoskeletal Injuries” DOD grant in collaboration with Georgia Tech, 2010-2013, Co-PI, $1,500,000 (GSU portion: $225,000). No-cost extension until 01/2014. “Interaction of Estrogen, Age and Activity on Musculoskeletal Strength in Females” NIH R01 grant in collaboration with the University in Minnesota, 2009-2014, Co-PI, $1,832,010 (GSU portion: $109,766). No-cost extension until 02/2015. “A Bone-Sparing Strategy for Muscular Dystrophies” grant, Muscular Dystrophy Association, 2009-2011, Co-PI, $253,024 (GSU portion: $0). “Energy Drink Formulation: Improving Fighter Pilot Performance in the Cockpit” grant, U.S. Air Force / Coca Cola, 2007-2009, PI, $130,032. “Skeletal Muscle Regeneration Enhancement by Early Administration of Immunotherapies” grant, DOD/U.S. Army Institute of Surgical Research, 2007-2010, PI, $276,039. “Myosin Structure and Strength Alterations in Aging Females” NIH R03 grant, 2006-2009, Co-PI, $100,000. Fellowships from CDC/NIOSH and the Oak Ridge Institute for Science and Education supporting summer research at NIOSH, 2001-2008, $101,000. “Chemokine Modulation of Skeletal Muscle Recovery from Injury” contract, Centers for Disease Control and Prevention (CDC) / National Institute for Occupational Safety and Health (NIOSH), 2004-2005, PI, $18,998. “Increasing the Efficiency of Exercise Countermeasures for Bone Loss” grant, National Space Biomedical Research Institute, 2004-2008, Consultant, $1,788,905. “Muscle Function Testing in Transgenic Mice” contract, CDC/NIOSH, 2001-2002, PI, $19,999. “Bone and Muscle Recovery from Simulated Microgravity” grant, National Space Biomedical Research Institute, 2001-2003, Consultant, $630,913. “Evaluation of Wheelchair Basketball Players in the 2000 Roosevelt International Basketball Camp”, Roosevelt-Warm Springs Institute for Rehabilitation, 2000, Co-PI, $8,500. “Kinematical Analysis of Wheelchair Propulsive Technique and Wheelchair Tennis Stroke Technique in the 1999 International Roosevelt Cup” grant, Roosevelt-Warm Springs Institute for Rehabilitation, 1999, Co-PI, $3,800. “Eicosanoid Production in Injured Mouse Muscles” contract, Proctor & Gamble, 1995, Co-PI, $11,669. “Mechanisms of Exercise-Induced Muscle Fiber Injury” NIH R01 grant, 1994-1997, Co-PI, $602,412. External (research; applied for but no final decision as of yet) None External (research; applied for but not funded) “Impact of Intensity, Duration, Frequency, and Onset of Mechanical Stimulation on Functional Recovery from Traumatic Muscle:Bone Injuries”, Department of Defense grant proposal submitted in February 2014 in collaboration with Georgia Tech, Co-PI, requested $296,299 for GSU portion. “The Impact of Physical Activity on Arthritis: A Systematic Review of Systematic Reviews”, Arthritis Foundation grant proposal submitted May 2013 in collaboration with the School of Public Health, Co-PI, requested $95,231. “Georgia Tech Biomechanics and Physiology Assessment and Education Program”, CSX Transportation contract proposal submitted May 2013 in collaboration with Georgia Tech, Co-PI, requested $182,599 for GSU portion. “Contraction-Induced Loss of Plasmalemma Excitability in Dystrophic Muscle”, NIH R01 grant proposal submitted Fall 2012 in collaboration with the University in Minnesota, Co-PI, requested $398,891 for GSU portion. “Skeletal Muscle Regeneration Enhancement by Early Administration of Immunotherapies”, Defense Advanced Research Projects Agency grant proposal submitted January 2005, PI, requested $501,555. “Acute and Chronic Effects of Exercise-Induced Muscle Injury on Thermoregulation and Performance in the Heat: Modification by Nutritional Intervention”, Department of Defense grant proposal submitted Spring 2003, PI, requested $1,427,720. “Countermeasures against Muscle Injury after Unloading”, National Space Biomedical Research Institute grant proposal submitted Summer 2000, Co-PI, requested $716,087. “Molecular Physiology of Recovery from Muscle Atrophy”, NIH R01 grant proposal submitted Spring 2000, Co-PI, requested $740,435. “Satellite Cell Role in Contraction-Induced Muscle Injury”, NIH R01 grant proposal submitted Fall 1999, PI, requested $707,222. “Work-Induced Muscle Injury: Effect of Activity on Muscle Strength Recovery and Protein Metabolism”, American Physical Therapy Association grant proposal submitted Fall 1998, Co-PI, requested $39,081. Internal (research; funded proposals) “Examining Spatial Heterogeneity of Muscle Inactivation Following Repair of the Anterior Cruciate Ligament”, GSU Research Team Grant, 2009, PI, $14,780. “Physical Therapy Enhanced Student Learning Labs”, GSU Student Technology Fee Funds, 2006, PI, $42,118. “Technology-Enhanced Clinical Instruction in Physical Therapy”, GSU Student Technology Fee Funds, 2006, Co-PI, $49,448. “How Does Mouse Skeletal Muscle Protect Itself from Exercise-Induced Muscle Injury?”, GSU Research Team Grant, 2001, Co-PI, $11,683. “Identifying Satellite Cell Activation and Commitment to Differentiation in the Recovery from Work- and ExerciseInduced Muscle Injury”, GSU College of Health and Human Sciences intramural grant, 1999, PI, $2,134. “Development of a Cell Culture-Based Model of Exercise- and Work-Induced Muscle Injury”, GSU College of Health and Human Sciences intramural grant, 1998, PI, $5,000. “Temperature Dependence of Functional Deficits Following Work- and Exercise-Induced Muscle Injury”, GSU Quality Improvement Funds, 1998, PI, $10,000. Scholarly Activities with Students: Student awards Supervised the conduct of a research study that was presented by Emily Lloyd (3rd year DPT student) at the 2016 Combined Sections Meeting of the American Physical Therapy Association; the study was selected as one of the top eight by the Acute Care Section of the APTA. Supervised the conduct of a research study that was presented by Thomas Ganas (3rd year DPT student) at the 4th Annual Regenerative Rehabilitation Symposium, Rochester, MN, 2015; Thomas won a $500 travel award to present the research at the conference. Supervised the conduct of a research study that was presented by Justin Howe (3rd year DPT student) at the 2015 Fall meeting of the Physical Therapy Association of Georgia; the study won the student research award along with a $300 award. Supervised the conduct of a research study that was presented by William Jones (2nd year DPT student) at the 2nd Annual Regenerative Rehabilitation Symposium in Pittsburgh, PA (November, 2012); the study won 2nd place in the student research award competition along with a $300 award. Supervised the conduct of a research study that was presented by Steven Fridenmaker (3rd year DPT student) at the 2010 Fall meeting of the Physical Therapy Association of Georgia; the study won the student research award along with a $300 award. Supervised the conduct of a research study that was presented by Rob Maresca (3rd year DPT student) at the 2008 Fall meeting of the Physical Therapy Association of Georgia; the study won the student research award along with a $350 award. Supervised the conduct of a research study that was presented by Melinda Heringer (3rd year MPT student) at an international conference on spinal cord injury (XXIIIrd International Symposium of the Center for Research in Neurological Sciences at Université de Montréal, May 6-8, 2001); Melinda Heringer was awarded a $1000 travel grant by the conference organizers. Supervised the conduct of a research study that was presented by Amy Long (3rd year MPT student) at the 2001 annual meeting of the Physical Therapy Association of Georgia; the presentation won the best “student presentation” award along with a $325 award. Dissertation committees Cheryl Lau, Department of Biomedical Engineering, Georgia Tech, Committee Member, 2016 – present. W. Michael Southern, Department of Kinesiology, University of Georgia, Committee Member, 2016 – present. Alice Li, Department of Biomedical Engineering, Georgia Tech, Committee Member, 2012 - 2014. Chia Hsu, School of Applied Physiology, Georgia Tech, Committee Member, 2011 - 2014. Namrita O’Dea, School of Applied Physiology, Georgia Tech, Committee Member, 2010 - 2015. Shikhar Vohra, School of Applied Physiology, Georgia Tech, Committee Member, 2008 - 2009. Scott Conger, School of Applied Physiology, Georgia Tech, Committee Member, 2008 - 2009. Jill Rahnert, School of Applied Physiology, Georgia Tech, Committee Member, 2007 - 2013. Herb Silver, Rocky Mountain University of Health Professions, Committee Member, 2007 - 2009. Amy L. Moran, Department of Kinesiology, University of Minnesota, Reader, 2004 - 2006. Wan Chen, School of Exercise & Sport Science at the University of Sydney, Committee Member, 2004 - 2005. Talal Nofal, Department of Kinesiology and Health, Committee Member, 2001 - 2005. C. Scott Bickel, Department of Exercise Science, University of Georgia, Committee Member, 2000 - 2002. Thesis committees Tara Mader, Department of Kinesiology, University of Minnesota, Committee Member, 2010 – 2011. Nicole Hopper, Department of Kinesiology and Health, Co-committee Chair, 2003 - 2004. Robin Kruger, Department of Kinesiology and Health, Co-committee Chair, 2003 - 2004. Rijuta Dhere, Department of Physical Therapy, Committee Chair, 2002 - 2003. Talal Nofal, Department of Physical Therapy, Committee Chair, 1998-1999. Other student honors projects Karen Rogers and Kelly Billings, MPT students in Department of Physical Therapy, Project title: CK-MM autoantibodies after skeletal muscle injury. Supervised this research project that was presented at a national-level conference (American College of Sports Medicine annual meeting). Completed Fall, 2003. Ruth Maher, Jenny Crute, Kim Green Beth Taylor, Alicia Tudor, and Tami Yudis, 3rd year MPT students in Department of Physical Therapy, Project title: Plantar pressures and muscle activation patterns during treadmill walking in able-bodied men. Supervised this research project that was presented by the students at a state-level conference (Physical Therapy Association of Georgia annual meeting). The data from this project went on to be published as an article in the journal Gait & Posture. Completed Fall, 2002. Other contributions to student accomplishments Coordinated the first seven Annual MPT Student Research Conferences (2000-2006), which are held the first week in December each year in the Speakers Auditorium; these conferences represent the culmination of research projects done by 3rd year MPT students in PT 7061. Organized and ran the Physical Therapy department's weekly faculty and student seminar series during 1999 and 2000. Presented Papers and Posters (partial listing; does not include presentations associated with items listed above under Scholarly Proceedings/Conference Abstracts): “Meta-analysis: what it can do for you and what it can’t”. Presented at the GSU Developmental Psychology seminar, January 21, 2015 (Invited Seminar). “The world of anti-inflammatories and skeletal muscle”. Presented by Kathy Myburgh, Carrie Smith, Kim Rainsford, and Gordon Warren at the annual meeting of the American College of Sports Medicine, May 30, 2013 (Refereed Symposium). “Impairments of skeletal muscle function: some causes, some differences, and few treatments”. Presented at the Program of Rehabilitation Sciences at the University of Minnesota, August 7, 2012 (Invited Seminar). “Impairments of skeletal muscle function: some causes, some differences, and few treatments”. Presented at the annual meeting of the Southeast Chapter of the American College of Sports Medicine, February 11, 2012 (Invited Lecture as part of Henry J. Montoye Scholar award). “Effect of caffeine ingestion on muscular strength and endurance: a meta-analysis”. Presented at the International Coffee, Caffeine and Sports conference in Lisbon, Portugal, December 4, 2010 (Invited Tutorial). “Caffeine ergogenicity: current perspectives regarding mechanisms”. Presented by Asker Jeukendrup, Gordon Warren, Lawrence Spriet, and Pat O’Connor at the annual meeting of the American College of Sports Medicine, June, 2010 (Refereed Symposium). “Skeletal muscle injury and repair: cellular mechanisms and physiological implications”. Presented by Maria Urso, Gordon Warren, Richard Lovering, and Susan Brooks at the annual meeting of the American College of Sports Medicine, June, 2010 (Refereed Symposium). “Effect of estradiol on inflammation following traumatic muscle injury”. Presented at the Program of Rehabilitation Sciences at the University of Minnesota, October 21, 2009 (Invited Seminar). “Impact of exercise on inflammation in acutely- and chronically-injured skeletal muscle”. Presented at the American Physiological Society and the American College of Sports Medicine “Integrative Biology of Exercise” joint meeting, September 27, 2008 (Invited Symposium). “Does increased muscular strength explain the ergogenic effect of caffeine during endurance exercise?”. Presented at the annual meeting of the American College of Sports Medicine, May 31, 2008 (Refereed Tutorial). “Ergogenic effect of caffeine during endurance exercise: metabolism vs. muscle function?”. Presented at the School of Applied Physiology at Georgia Tech, April 3, 2008 (Invited Seminar). “Does increased muscular strength explain the ergogenic effect of caffeine during endurance exercise?”. Presented at the annual meeting of the Southeast Chapter of the American College of Sports Medicine, February 16, 2008 (Refereed Tutorial). “Voluntary run training but not estradiol deficiency alters the bone:muscle functional relationship in mice”. Presented at the U.S. Army Research Institute of Environmental Medicine in Natick, MA, September 28, 2007 (Invited Seminar). “Basic science of inflammation after acute skeletal muscle injury”. Presented at the Medical College of Georgia in Augusta, GA, April 12, 2007 (Invited Seminar). “Inflammation after acute musculoskeletal injury: basic science and clinical perspectives”. Presented by G.L. Warren, J. Kercher, and L.Y. Griffin at the annual meeting of the Southeast Chapter of the American College of Sports Medicine, February 9, 2007 (Refereed Symposium). “Caffeinated sports drink: ergogenic effects and possible mechanisms”. Presented at the U.S. Army Military Academy in West Point, NY, June 16, 2006 (Invited Seminar). “Inflammation after acute musculoskeletal injuries: friend or foe?”. Presented by G.L. Warren, P.G. Brolinson, F.X. Pizza, and Y.L. Griffin at the annual meeting of the American College of Sports Medicine, June 3, 2006 (Refereed Symposium). “Cytokine and chemokine modulation of the recovery from acute muscle injury”. Presented at the U.S. Army Institute of Surgical Research in San Antonio, TX, March 8, 2006 (Invited Seminar). “Cytokine and chemokine modulation of the recovery from acute muscle injury”. Presented at the 5th Annual Dr. S. Mouchly Small Muscle Symposium at the University at Buffalo, NY, June 23, 2005 (Invited Seminar). “How do macrophages modulate satellite cell activity (and vice versa) during the recovery from skeletal muscle injury”. Presented at the School of Applied Physiology at Georgia Tech, February 24, 2005 (Invited Seminar). “Inflammatory mediators: friend or foe following muscle injury”. Presented at the Department of Exercise Science at the University of Georgia, April 21, 2004 (Invited Seminar). “Does inflammation help or hurt in the recovery from muscle injury?”. Presented at the annual meeting of the Southeast Chapter of the American College of Sports Medicine, January 31, 2003 (Refereed Tutorial). “Does inflammation help or hurt in the recovery from muscle injury?”. Presented at the Department of Exercise Science at the University of Massachusetts at Amherst, September 27, 2002 (Invited Seminar). “Satellite cell activation and commitment to differentiation: comparison of contraction-induced and traumatic muscle injuries”. Presented at the Department of Health & Kinesiology at Texas A&M University, March 2, 2001 (Invited Seminar). “Satellite cell activation and commitment to differentiation: comparison of contraction-induced and traumatic muscle injuries”. Presented at the National Institute for Occupational Safety and Health in Morgantown, WV, February 8, 2001 (Invited Seminar). “Strength loss from work- and exercise-induced muscle injury: contributing factors and their relative importance”. Presented at the Department of Cellular Biology & Anatomy at the Medical College of Georgia, January 9, 2001 (Invited Seminar). “Soft tissue pathomechanics and its application to ergonomics”. Presented by R.G. Cutlip, G.L. Warren, W.T. Stauber, and D. Rempel at the annual meeting of the International Association of Ergonomics, August 3, 2000 (Refereed Symposium). “Skeletal muscle adaptations and rehabilitation”. Presented by L.V. Thompson, G.L. Warren, D.A. Lowe, and R.K. Shields at the annual meeting of the American Physical Therapy Association, June 17, 2000 (Refereed Educational Session). “Eccentric contraction-induced strength loss: contributing factors and their relative importance”. Presented at the National Institute for Occupational Safety and Health in Morgantown, WV, March 8, 2000 (Invited Seminar). “What exactly is exercise-induced muscle injury and how do we measure it?”. Presented by G.L. Warren and C.P. Ingalls at the annual meeting of the Southeast Chapter of the American College of Sports Medicine, January 29, 2000 (Refereed Tutorial). “Eccentric contraction-induced strength loss: contributing factors and their relative importance”. Presented by G.L. Warren, C.P. Ingalls, and R.B. Armstrong at the annual meeting of the Southeast Chapter of the American College of Sports Medicine, January 30, 1999 (Refereed Tutorial). “Strength loss in contraction-induced muscle injury”. Presented at the Department of Biology at Georgia State University, April 30, 1999 (Invited Seminar). “Mechanisms underlying the strength deficit following work- and exercise-induced muscle injury”. Presented at the Department of Cell Biology at Emory University, March 17, 1999 (Invited Seminar). Honors and Awards: Selected as the Henry J. Montoye Scholar for the Southeast Chapter of the American College of Sports Medicine, 2011 Selected as Fellow of the American College of Sports Medicine, 2005 Selected as Principal Investigator for the National Space Biomedical Research Institute, 1997 Selected for Who’s Who in American Science, 1993 Selected as U.S. Army Reserve Officer (Captain) to serve as the Emergency Deployment Facilities Engineer at Eisenhower Army Medical Center, Fort Gordon, Georgia, 1988-1991 Recipient of University-wide Graduate Research Assistantship at the University of Georgia, 1987-1989 Selected as U.S. Army Reserve Officer (Captain) to serve as the Assistant Health Physics Officer at Martin Army Medical Center, Fort Benning, Georgia, 1986-1987 Elected member of Phi Kappa Phi, Tau Beta Pi, and Sigma Xi Honor Societies, 1986 U.S. Army Achievement Medal, 1984 Top Graduate at the U.S. Army Nuclear, Biological, and Chemical Course, 1982 Graduate of the U.S. Army Airborne (Parachute) School (1979), U.S. Army Ranger School (1981), and U.S. Army Jungle Warfare School (1981) Honor Graduate of the U.S. Army Engineer Officer Basic School, 1980 Engineer-In-Training, State of Georgia, 1980 Graduate with Highest Honors, Georgia Institute of Technology, 1980 Distinguished Military Graduate, Georgia Institute of Technology, 1980 Awarded U.S. Army Reserve Officer Training Corps (ROTC) College 4-Year Scholarship, 1976-1980 Service to the University, College, and Academic Unit: University Promotion and Tenure Manual Committee, Committee member, 2015-present. University Triennial Evaluation of Associate Provost for Strategic Initiatives and Innovation, Committee member, 2015. Byrdine F. Lewis School of Nursing and Health Professions; Triennial Faculty Evaluation of Associate Dean of Research, Committee member, 2014-2015. Department of Physical Therapy, Search Committee for Faculty Vacancy; Committee member, 2014-2015. Byrdine F. Lewis School of Nursing and Health Professions; Dean’s Senior Faculty Advisory Committee; Committee member, 2014. Byrdine F. Lewis School of Nursing and Health Professions; Triennial Faculty Evaluation of Associate Dean of Academic Affairs, Committee co-chair, 2014. Byrdine F. Lewis School of Nursing and Health Professions; Post-Tenure Review Committee; Committee co-chair, 2013-2014. Byrdine F. Lewis School of Nursing and Health Professions; Promotion and Tenure Committee; Committee chair/member, 2013-present. Department of Physical Therapy, Search Committee for Academic Coordinator of Clinical Education; Committee member, 2012-2013. Department of Physical Therapy, Search Committee for Department Chair; Committee co-chair, 2012-2014. Department of Physical Therapy, Search Committee for Faculty Vacancy; Committee co-chair, 2012-2013. Byrdine F. Lewis School of Nursing and Health Professions; Strategic Planning Committee; Committee chair, 2012. Byrdine F. Lewis School of Nursing and Health Professions; PhD Exploratory Committee; Committee member; 2011present. Byrdine F. Lewis School of Nursing and Health Professions; Research Committee; Committee chair, 2011-2013. Division of Health Professions; Research Committee; Committee chair, 2011-2014. Department of Physical Therapy, Search Committee for Faculty Vacancy; Committee member, 2011-2012. School of Health Professions, Triennial Faculty Evaluation of School Chair, Committee chair, 2011. Department of Physical Therapy, Student Retention Committee; Committee member, 2010-present. Department of Physical Therapy, Search Committee for Faculty Vacancy; Committee chair, 2010. Department of Physical Therapy, Search Committee for Faculty Vacancy; Committee chair, 2009-2010. Department of Physical Therapy, Search Committee for Faculty Vacancy; Committee chair, 2009-2010. Department of Physical Therapy, Search Committee for Faculty Vacancy; Committee chair, 2009-2010. University’s Capital Budget and Space Allocation Committee (subcommittee on research space allocation); Committee member, 2009-2010. University’s Laboratory Safety Committee, Committee member, 2008-2011. College of Health and Human Sciences, Strategic Planning Committee (research subcommittee); Committee member, 2008-2009. Department of Physical Therapy, Search Committee for Faculty Vacancy; Committee member, 2008-2009. Department of Physical Therapy, Triennial Faculty Evaluation of Division Director, Committee chair, 2008. School of Health Professions, Promotion and/or Tenure Committee, Committee chair and member, 2007-2013. School of Health Professions, Academic Program Review Committee, Committee member, 2007-2008. College of Health and Human Sciences, Research Committee; Committee chair, 2004-2011. Department of Physical Therapy, Research Committee; Committee chair, 2005-2011. College of Health and Human Sciences, Promotion and/or Tenure Committee for Professors, 2005-2006. Department of Physical Therapy, Director of the MS in Health Sciences (PT option) program, 2004-2006. Department of Physical Therapy, Search Committee for Faculty Vacancy; Committee member, 2003-2004. University’s URSA Internal Research Grant Review Committee; Committee member, 2001-2003, 2004-2006, and 2010-present. Department of Physical Therapy, Ad hoc committee formed to generate and conduct a survey soliciting opinions on the proposed Doctor of Physical Therapy program; Committee member, 2001. University’s federally-mandated Institutional Animal Care and Use Committee; Committee member, 2000-2002. Service Activities in Professional Organizations and Service to the Profession: Regular Member, American Physiological Society Fellow, American College of Sport Medicine American College of Sport Medicine Research Review Committee, Committee member, 2008-2009. American Federation for Aging Research (AFAR) National Scientific Advisory Council, Committee member, 2005present. Assistant Editor, Exercise and Sport Sciences Reviews, 2005-2013. Served as manuscript reviewer for the American Journal of Physiology, Archives of Physical Medicine and Rehabilitation, Aviation, Space, & Environmental Med Biological Research for Nursing, Canadian Journal of Applied Physiology, Cells, Tissues, & Organs, Clinical Science, European Journal of Applied Physiology, Hormone Research, International Journal of Sport Nutrition & Exercise Metabolism, Journal of Applied Physiology, Journal of Athletic Training, Journal of Biomechanics, Journal of Musculoskeletal and Neuronal Interactions, Journal of Physiology, Journal of Strength and Conditioning Research, Medicine and Science in Sport and Exercise, Muscle and Nerve, PloS ONE, Research Quarterly for Exercise and Sport, and Sports Medicine. Served on grant proposal review panels for the American Federation for Aging Research, the National Institute for Occupational Safety and Health, the United Kingdom Government/Wellcome Trust, and the U.S. Army Medical Research and Materiel Command. Service to the Community: Prepared and conducted a 4-hour experience on laboratory techniques and procedures for the 3rd grade class from Heritage Preparatory School in Atlanta (May 18, 2001). Volunteer worker for Hosea Williams' Feed the Hungry and Homeless program (Christmas, 2000).
© Copyright 2025 Paperzz