66 – 67 Choice of donor Donor sperm Donor sperm required for fertility treatment is provided by the London Sperm Bank (LSB), the biggest and most successful donor bank in the UK. This is important because, before starting any treatment, patients must be matched with their chosen sperm donor. With the UK’s widest choice of sperm donor, you can be confident that you have the best chance of using a donor who matches your preferences. All LSB donors are carefully selected according to the rules laid out by the British Andrology Society, the British Fertility Society and the HFEA. The laboratory processes involved in the storage of the sperm samples also comply with the EU Tissue and Cell Directives. All donors must comply with the following basic criteria: • Have high sperm quality, including count, motility and morphology • Be aged between 18 and 41 years • Be in good general health • Have no personal or family history of genetic disease • Have no current sexually transmitted infection • Be fully informed of the HFE Act with regards to anonymity • Be resident in the UK for at least 12 months and be able to provide a copy of their passport • Agree for their GP to be contacted • Be fully aware of the medical history of their parents, grandparents, siblings and any other close family members. All donors are screened for the following: a) Before starting and during the programme, and on their final donation visit: • Gonorrhoea • Trichomonas • Chlamydia (in urine) • Semen bacterial culture • HIV I and II, Hepatitis B, Hep B Core and Hep C • CMV IgG and IgM • Syphilis • HTLV 1 and 2 b) Following clear screening for the tests above: • Blood group and Rhesus factor • Chromosome karyotype • Cystic fibrosis screen c) Donors of particular racial groups will also be tested for: • Sickle cell anaemia • Thalassaemia • Tay Sachs 68 – 69 Confidentiality All donors must complete a detailed physical examination with a fertility specialist, attend an implications counselling session and complete an interview with the LSB team. Donors are also required to complete a full set of consent forms, including HFEA ID Registration, Consent to Donation and Consent to Disclosure. Following a successful treatment cycle, some patients decide to reserve donor sperm samples for future treatment so that a sibling is genetically related to your child. Sibling sperm can also be used by a same sex partner. Some donors may decide to write a short paragraph about themselves which is made available to patients after the birth of a child. This is known as a ‘pen sketch’ and is intended to help when parents decide to talk to their children about their sperm donor. The process is very straightforward. After your pregnancy has been confirmed with a heartbeat seen on an ultrasound scan, you should contact the donor bank (sibling@lsbdonors.com) to request to reserve some samples for future use. In the event that no sibling sperm samples are available, the LSB will contact the donor to request that he returns for further donation, which will then be set aside for you. However, you should be aware that some donors decide not to return to donate further samples. As explained on page 19, donor sperm is most commonly used for intrauterine insemination (IUI). IUI with donor sperm is also the preferred fertility treatment method for lesbian and single women, who may also be treated as egg-sharing IVF patients using donor sperm for fertilisation. If you decide to have your future treatment with sibling sperm at an alternative clinic, we can arrange for the samples to be moved. This is relatively straightforward if moved to an HFEA-licensed clinic in the UK, but may be more complicated if you wish to transfer the samples overseas. All samples are quarantined for six months post donation and not released for use until all tests listed in a), b) and c) are complete and satisfactory. As with donor eggs and embryos, the HFEA keeps a confidential register of information about donors, patients and treatments. Today, a donor-conceived person has the right to access: • Non-identifying information about the donor and any donor-conceived genetic siblings, from the age of 16 • Identifying information about the donor (where applicable), from the age of 18 Sperm donor requests Donors of sperm, eggs and embryos can request information at any time about any children born as a result of their donation. They can receive information about the number of children born as a result of their donation, their sex and the years of birth. Donors seeking information about children born as a result or their donation may find counselling or similar support services helpful in considering the implications of receiving such information. • Identifying information about donor- conceived genetic siblings, with mutual consent, from the age of 18 Donor sperm from other sources In the unlikely event that we are unable to meet your requirements from donors recruited at the LSB, there are a number of other options available to you. These include purchasing sperm from another UK centre and importing sperm from overseas. Both can be done, provided that procedures are in accordance with HFEA requirements. Patients considering sperm from overseas clinics should ensure that the donor is UK and HFEA compliant. For example, the donor should have completed all screening tests and shipping should meet the requirements of the HFEA. Known donor sperm We have an extensive and very successful ‘known donation programme’. Known donors can be a friend or non-blood relation brought to the clinic by a patient for her own use. As with the HFEA, we do not recommend the use of donors recruited from websites or through recruitment agents unless they are prepared to fully disclose their details to the patient and clinic. Your known donor is required to undergo the same screening as an anonymous donor (including all tests, quarantine and consents). In addition he should also agree to all anonymity requirements and be fully aware of the legal implications of his status as a ‘known donor’. This is particularly important if the patient is a single woman. Patients are strongly advised to seek legal advice before agreeing to any contact or co-parenting arrangements with a known donor if single or a lesbian couple (including those who are lesbian civil partners). However, known donors are not subject to the same requirements for sperm quality or age, so known donors with poor quality sperm will not be excluded from the programme – although it would be suggested that ICSI might be more successful than IUI. Known donors over the age of 41 years will be considered, but only following a medical examination with one of our consultants. The reception area at LWC London Checklist for those using donor sperm • Book your initial consultation at the LWC or Bridge Centre • Agree your treatment plan with your specialist • Visit the London Sperm Bank website • Choose and confirm the characteristics of your donor • If sourcing donor sperm from an outside clinic, ensure that the donor complies with all UK and HFEA requirements • Seek legal advice before making any decisions about using a known sperm donor. • Avoid the use of sperm donors recruited from websites or recruitment agents unless full donor details can be made available to you and the clinic • Once your pregnancy is confirmed, consider reserving additional donor sperm for genetically related siblings before treatment takes place
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