Society of Chinese Bioscientists in America You must type or sign your name on this ballot for your votes to be counted. All votes will be kept strictly confidential. Name of Member________________________________ 2017 ELECTION BALLOT OFFICE 1. PRESIDENT: (VOTE FOR 1) (Jan. 1, 2020 - Dec. 31, 2021) 2. SECRETARY: (VOTE FOR 1) (Jan. 1, 2020 - Dec. 31, 2021) 3. TREASURER: (VOTE FOR 1) (Jan. 1, 2020 - Dec. 31, 2021) 4. COUNCILOR: (VOTE FOR 2) (Jan. 1, 2018 - Dec. 31, 2021) 5. NOMINATION COMMITTEE: NOMINEES VOTE (√) Lin Mei (Augusta University) _____ Hui Zheng (Baylor College of Medicine) _____ Bin Gao (NIAAA, Nat. Institutes of Health) _____ Lee Zou (Massachusetts General Hospital Cancer Center) _____ Ren-Ke Li (University of Toronto) _____ Yong Xu (Baylor College of Medicine) _____ Zhiyuan Shen (Rutgers The State University of New Jersey) _____ Mingyao Liu (University of Toronto) _____ Wei Yang (NIDDK, Nat. Institutes of Health) _____ Jing Zhou (Brigham and Women's Hospital, Harvard) _____ Yimin Zou (University of California, San Diego) _____ Wenyi Wei (Beth Israel Medical Center, Harvard) _____ Zhong-Ping Feng (University of Toronto) _____ Huilin Zhou (University of California, San Diego) _____ Yang Liu (National Children’s Medical Center) _____ Xiao-Jing Wang (University of Colorado) _____ Nan-Ping Weng (NIA, Nat. Institutes of Health) _____ Xue Sean Li (Boston Children’s Hospital, Harvard) _____ Ji Luo (NCI, Nat. Institutes of Health) _____ Li Yang (NCI, Nat. Institutes of Health) _____ Zhe Han (George Washington University) _____ Dong Wang (University of California, San Diego) _____ Victor Hsia (University of Maryland) _____ Boyi Gan (University of Texas MD Anderson Hospital) _____ (VOTE FOR 6) (Jan. 1, 2018 - Dec. 31, 2019) 6. MEMBERSHIP COMMITTEE: (VOTE FOR 6) (Jan. 1, 2018 - Dec. 31, 2019) Please return your signed BALLOT by May 21, 2017 via e-mail attachment to SCBA Co-Executive Director, Chris Lau: chris.lau@ucsf.edu and The SCBA Treasurer, Ying Zhang: yingezhang@gmail.com Election Candidates 2013 Society of Chinese Bioscientists in America Election Candidates June 2013 NOMINEES FOR SCBA PRESIDENT LIN MEI, Ph.D. Current Positions: Professor and Chair, Department of Neuroscience and Regenerative Medicine, Medical College of Georgia Education: Diploma of Medicine, 1982, Jiangxi Medical College (now Nanchang University), China MS (Neuropharmacology), 1985, Institute of Pharmacology & Toxicology, Beijing, China. PhD (Pharmacology and Toxicology), 1989, University of Arizona. Postdoctoral Fellow, Department of Neuroscience, Johns Hopkins University, School of Medicine. Appointments: 1994-1999, Assistant Professor, Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia 1999-2002, Assistant Professor; 2002-2004 Associate Professor, Neurobiology, Pathology, and Physical Medicine and Rehabilitation, University of Alabama at Birmingham, Birmingham, Alabama 2004-present, Professor of Neurology; 2009-2014, Director of Institute of Molecular Medicine and Genetics; 2014-present, Professor and Chair (Inaugural), Department of Neuroscience and Regenerative Medicine, Medical College of Georgia Research Interest: I am interested in synapse formation and plasticity. Our research contributes to a better understanding of pathophysiological mechanisms of neuromuscular disorders such as myasthenia gravis and brain disorders including schizophrenia, bipolar disorder, and autism. Service to SCBA: Life-time member (since 2004; member since 1994). 2009, Co-Chair, Program Committee of 2009 SCBA International Symposium, Taipei. 2011, Session Chair, 13th SCBA International Symposium, Guangzhou, China. 2014 – Present, Associate Editor, Cell & Bioscience. 2016 – Present, Councilor 2016 – 2017, Chair of Program Committee of 2017 SCBA International Symposium, Hangzhou Non-SCBA, Non-institutional Service: Society for Neuroscience (SfN), Membership and Chapters Committee, 2007-2010; Achievement Awards Selection Committee, 2010 – 2012; Chinese Biological Investigators Society (CBIS), Treasurer, 2006 – 2010; American College of Neuropsychopharmacology (ACNP), Program Committee (2015 - present); Editorial member of 9 journals including Journal of Neuroscience; Chair, Gordon Research Conference on Molecular and 1 Election Candidates Cellular Neurobiology, Hong Kong, 2012; Chair, 2013 Symposium on Synapse Formation, SfN 2015 Annual Meeting in2013 Chicago. Selected Honors: 1987, Honorary Citizen of Tucson, the City of Tucson, Arizona; 2004, Outstanding Young Investigator Award (Type B), National Natural Science Foundation, China; 2004, Georgia Research Alliance Eminent Scholar in Neuroscience; 2005, Chung Kong (Chang Jiang) Scholar, Li Ka Shing Foundation of Hong Kong and Ministry of Education, China; 2008, Mathilde Solowey Lecture Award in Neurosciences, Foundation for Advanced Education in Sciences at NIH; 2008, Distinguished Investigator, National Alliance for Research on Schizophrenia and Depression (NARSAD); 2009, Alberta Heritage Foundation for Medical Research Visiting Lecturer; 2011, Thousand Talents Scholar (Type B), Central Coordination Committee on the Recruitment of Talents Project, China; 2014, Fellow, American Association for the Advancement of Science (AAAS). HUI ZHENG, Ph.D. Current Position: Huffington Foundation Endowed Chair in Aging Director, Huffington Center on Aging Professor, Department of Molecular and Human Genetics, Baylor College of Medicine Education and Training: 1980-1884, B.S., Chemistry, Peking University, Beijing, China 1985-1990, Ph.D., Biochemistry, Baylor College of Medicine, Houston, Texas 1990-1991, Postdoctoral Fellow, Genetics, Baylor College of Medicine, Houston, Texas Appointments: 1991-1995, Senior Research Biologist; 1995-1999, Research Fellow, Merck & Co. Inc., Rahway, New Jersey 1999-2002, Assistant Professor, Department of Molecular and Human Genetics, Baylor College of Medicine 2002-2006, Associate Professor, Department of Molecular and Human Genetics, Baylor College of Medicine 2006-present, Professor, Department of Molecular and Human Genetics, Baylor College of Medicine 2010-present, Director, Huffington Center on Aging, Baylor College of Medicine Research Interests: My laboratory has a long-standing interest in understanding the pathophysiological mechanisms leading to Alzheimer’s disease. The combination of industry and academic experience afford me a unique perspective in both basic research and drug development. Our main interest currently is to understand the role of the autophagy and lysosomal pathway and neuronimmune interaction in disease pathogenesis and therapy development. SCBA Services: • SCBA-Texas Chapter 2007-2008: President-elect, SCBA-Texas Chapter 2008-2009: President, SCBA-Texas Chapter Major responsibilities: a) In charge of Chapter communications and bi-weekly evening faculty research social; b) Organized and chaired the Chapter annual symposium consisting of plenary and keynote presentations, trainee presentations and judging, and election; c) Organized a fundraising effort and raised ~$17,000 for the Sichuan earthquake disaster relief. 2006-present: Member of the organizing committee of the SCBA-Texas annual symposium. 2 Election Candidates 2013 • National SCBA 2012-2017: Council member, SCBA 2014-2015: Treasurer, SCBA Major responsibilities: a) In charge of the SCBA financial transactions, book-keeping, tax returns, and SCBA nonprofit status filing; b) Co-Chaired the Nomination Committee with Dr. Kun-Liang Guan; c) Worked with SCBA President Dr. Dihua Yu and Secretary Dr. Gensheng Feng and others in the leadership team to organize the 2015 SCBA biennial conference in Taipei. Non-SCBA Services and Leadership Positions: 2003-2007: Member, 2007-2008: Chair, Neuroscience of Aging Review Committee, NIA/NIH 2013: Co-organizer, Keystone Symposium, Alzheimer’s disease, Keystone, Colorado 2010-2016: Member, Cellular & Molecular Neurodegeneration (CMND) Study Section, NIH 2008-2017: Member, 2017-present: Co-Chair, Scientific Advisory Committee, BrightFocus Foundation 2009-present: Co-Chair, Program Committee, International Conference on Molecular Neurodegeneration: Xiamen, China, 2009; Shanghai, China, 2011; Cannes, France, 2013; Seoul, Korea, 2016; Stockholm, Sweden, 2018. 2011-present: Member, Medical and Scientific Advisory Council, Alzheimer’s Association NOMINEES FOR SCBA SECRETARY BIN GAO, MD, PhD. BIN GAO, MD., PhD Current Position: Chief, Laboratory of Liver Diseases NIAAA, NIH Education and training: MD.: Wannan Medical College, China 1986 PhD: Norman Bethune Medical University, 1991 Postdoctoral Fellow: 1991-1992: NIH; 1992-1995: Medical College of Virginia Previous Positions: 1995-2000: Assistant Professor (Tenure track), Department of Pharmacology/Toxicology, Medical College of Virginia 2000-2005: Tenure track investigator, Chief, Section on Liver Biology, NIAAA, NIH 2005-2009: Senior Investigator, Chief, Section on Liver Biology, NIAAA, NIH 2009-present: Senior Investigator, Chief, Laboratory of Liver Diseases, NIAAA, NIH Research Interest: Immunological aspects and molecular pathogenesis of liver diseases Hepatic inflammation and immunity in liver diseases Novel therapeutic targets of alcoholic and nonalcoholic liver diseases Past service to SCBA: 2010-2011: President, SCBA DC-Baltimore chapter 2011: Organizer and Chair: SCBA local chapter and NIAAA joint symposium on Digestive Diseases, NIH 2011: session organizer and chair: Stem cell symposium at the Annual CBA meeting, MD 2011: session organizer and chair, The 13th SCBA International Conference, Guangzhou 2015-16: SCBA nomination committee 2015: session chair, the first SCBA DC-Baltimore chapter symposium 3 Election Candidates 2013 Selected Honors and Awards: 1991: Forgarty International Visiting Fellow Award, NIAAA, NIH 2000: International Society for Biomedical Research on Alcoholism (ISBRA) Junior Investigator Award 2002: Elected to the American Society for Clinical Investigation (ASCI) Member 2008: Named as the member of Senior Biomedical Research Service (SBRS) by NIH director 2010: NIH Asian & Pacific Islander American Organization (APAO) award LEE ZOU, Ph.D. Current Positions: Professor of Pathology (tenured), Harvard Medical School Associate Scientific Director, Massachusetts General Hospital (MGH) Cancer Center James and Patricia Poitras Endowed Chair in Cancer Research Education and training: 1992 B.S. in biochemistry, Sun Yat-Sen University, China 1994 M.S. in biochemistry, Kansas State University 1999 Ph.D. in molecular genetics, Stony Brook University & Cold Spring Harbor Laboratory 2000-3 Postdoc fellow, HHMI/Baylor College of Medicine 2003-4 Postdoc fellow, HHMI/Harvard Medical School Research interest: The research of my laboratory is focused on understanding how genomic integrity is maintained in normal cells and how genomic instability arises in cancer cells. In addition, we seek to identify new ways to exploit the genomic instability in cancer cells for cancer therapy. I and my colleagues have extensively studied how DNA damage is sensed and signaled in human cells. In particular, we have made important contributions to the understanding of how the ATR checkpoint pathway is activated by DNA damage and DNA replication problems. Our work has laid the foundation for current models of DNA damaging signaling and DNA damage responses. My lab has also identified specific vulnerabilities in distinct subsets of cancers that render cancer cells susceptible to inhibition of the ATR checkpoint. These studies have provided new opportunities for targeted cancer therapy. Past Service to SCBA: 2014-5 Elected Member, the SCBA Membership Committee 2017 Keynote Speaker, Annual Symposium of the SCBA Texas Chapter Selected Services, Honors and Awards: 2000 Fayez Sarofim Fellow (named fellow), the Damon Runyon Cancer Research Fund 2004 The Smith Family New Investigator Award, the Medical Foundation 2005 V Scholar, the V Foundation for Cancer Research 2007 New Scholar in Aging, the Ellison Medical Foundation 2008 American Cancer Society Research Scholar 2009 The One Hundred Award, MGH Cancer Center 2009 Member, Faculty of 1000 2011 Member, Editorial Board, Molecular and Cellular Biology 2011 Scholar, Leukemia & Lymphoma Society 2011 The Jim & Ann Orr MGH Research Scholar 4 2011 2012 2014 2014 2015 2016 2016 Election Candidates Senior Scholar in Aging, the Ellison Medical Foundation Member, Editorial Board, Journal of Biological Chemistry The Breakthrough Award, Department of Defense Member, Editorial Board, Molecular Cell The Kraft Prize for Translational Research, MGH James & Patricia Poitras Endowed Chair in Cancer Research Member, Editorial Board, Cancer Research 2013 REN-KE LI, MD, PhD. FCAHS Professor of Surgery, University of Toronto Senior Scientist, University Health Network Toronto General Hospital, TMDT 3-702 101 College St., Toronto, ON, Canada M5G 1L7 Telephone: 416-581-7492, Fax 416-581-7493 E-mail: renkeli@uhnres.utoronto.ca Short Biography Dr. Ren-Ke Li, MD, PhD is a Professor of Medicine in the Department of Surgery, Division of Cardiac Surgery at the University of Toronto. Dr. Li is also a Senior Scientist at the Toronto General Research Institute, University Health Network working in the field of stem cell transplantation and tissue engineering. He is the recipient of the Canada Research Chair in Cardiac Regeneration (Tier 1) of the Canadian Institutes of Health Research and was a Career Investigator of the Heart and Stroke Foundation of Canada. Dr. Li has been on the forefront in the field of cell transplantation and tissue engineering. In 1996, he published the first demonstration that cells transplanted into myocardial scar tissue survived, differentiated into muscle tissue, and improved heart function. Over 25 years his research group has defined muscle cell transplantation for Cardiac Repair, followed by stem cell transplantation for Cardiac Regeneration. Both cell repair and regeneration technologies have been translated to clinical application at Phase I and II levels. Since the patients with heart failure are aged population, currently, his research group is attempting to determine the mechanisms by which transplanted cells exert their beneficial effects by Rejuvenation of aged stem cells and aged recipients. Clarifying these mechanisms of Repair, Regeneration and Rejuvenation will allow them to develop the “next generation” of cell therapy for restoration of heart function of aged patients. Because of his contribution to cardiovascular science, Dr. Ren-Ke Li was an elected Fellow of the Canadian Academy of Health Sciences, the International Academy of Cardiovascular Science and the Canadian Cardiovascular Society. He has received several national and international awards, including Scientific Award, Chinese American Medical Society; Clemson Award for Applied Research, Society for Biomaterials; Professional Achievement Award, Chinese Professionals Association of Canada; The Queen Elizabeth II Diamond Jubilee Medal, The Governor General of Canada; Premier’s Research Excellence Award, Ontario Ministry of Energy, Science and Technology; Lister Prize, University of Toronto; Mel Silverman Mentorship Award, University of Toronto. Dr. Li has published 232 peer-reviewed papers in very good Journals. He has been invited to contribute several commentaries and viewpoint articles and is an international opinion leader in his field. Dr. Li is a long time contributor to local SCBA activities. As a past President of the Toronto SCBA chapter, Dr. Li serves as a key executive committee member providing an important leadership role to the chapter. 5 Election Candidates NOMINEES FOR SCBA TREASURER 2013 YONG XU, Ph.D., M.D. Current Position: Associate Professor USDA/ARS Children’s Nutrition Research Center Department of Pediatrics Baylor College of Medicine Education and Training: 1994-1999, Bachelor of Medicine, Tongji Medical University, Wuhan, China 1999-2002, Master of Medical Science, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China 2002-2006, PhD, Cell Biology, University of Alberta, Edmonton, Alberta, Canada 2006-2009, Postdoctoral Fellow, Neuroendocrinology, UT Southwestern Medical Center, Dallas, Texas Appointments: 2009-2010 Instructor, Department of Internal Medicine, UT Southwestern Medical Center 2010-2016 Assistant Professor, Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine 2012-2016 Joint Assistant Professor, Department of Molecular and Cell Biology, Baylor College of Medicine 2016-now Associate Professor, Children’s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine 2016-now Joint Associate Professor, Department of Molecular and Cell Biology, Baylor College of Medicine Research Interests: The goal of my research is to identify the novel neural circuits, neurotransmitters and intracellular molecules in the brain that are critical for control of feeding behavior, body weight, glucose balance and blood pressure. I hope that results from my research will identify rational targets for developing therapeutic strategies for obesity, eating disorders, diabetes and hypertension. SCBA Services: • SCBA-Texas Chapter 2014-2015: President Assistant, SCBA-Texas Chapter 2015-2016: Secretary, SCBA-Texas Chapter Major responsibilities: a) In charge of Chapter communications; b) Circulate announcements of bi-weekly evening faculty research social; c) Participated in the organization of the Chapter annual symposium consisting of plenary and keynote presentations, trainee presentations and judging, and election; c) Participated in the organization of symposium in Baoding. 2014-present: Member of the organizing committee of the SCBA-Texas annual symposium. Non-SCBA Services and Leadership Positions: Chair for 2012 World Congress Endobolism Chair for 2015 ENDO Society, Regulation of feeding and lipid Chair for 2016 Keystone Symposium of Obesity Chair for 2017 SCBA National Conference, Metabolic diseases Ad Hoc Member, NIH, ZRG1 IFCN-H, May 2013 Ad Hoc Member, NIH, EMNR-P Review Group, March 2013 Ad Hoc Member, ADA Novo Nordisk Research Grant IH, May 2012 Ad Hoc Member, UK Diabetes, February 2012 Ad Hoc Member, UK Biotechnology and Biological Sciences Research Council, March 2017 Ad Hoc Member, UK Medical Research Council, March 2017 6 Election Candidates 2013 ZHIYUAN SHEN (沈 智 渊 ), PhD Current Positions • Professor of Radiation Oncology, Pharmacology • Chief, Division of Radiation Cancer Biology, Department of Radiation Oncology, Robert Wood Johnson Medical School, • Co-Leader, Genomic Instability and Cancer Genetics program, NCI designated comprehensive cancer center, Rutgers Cancer Institute of New Jersey, Rutgers The State University of New Jersey Education and Training 02/1994-09/1996: Directors Postdoctoral Fellowship of Los Alamos National Laboratory, Los Alamos, New Mexico, USA (mentor: David Chen) 01/1990-02/1994: PhD (05/1993) and Postdoc (02/1994), radiation and molecular biology, Colorado State University, Fort Collins, CO, USA (thesis advisor: Mortimer M. Elkind) 08/1985-08/1988: MS (radiation medicine and toxicology), Beijing Institute of Radiation Medicine, Beijing, China. (Thesis advisors: Wu De-Chang/吴德昌 and Ye Chang-Qing /叶常青) 09/1980-08/1985: MD, Norman Bethune University of Medical Sciences (presently Jilin University School of Medicine), Jilin, China Past Positions 05/2006 – Tenured Associate Professor (05/2006), Tenured Professor (07/2008), inaugural Chief (05/2006) of Division of Radiation Cancer Biology at Department of Radiation Oncology, and Co-leader (12/2008) of Genomic Instability and Cancer Genetic Program, NCI Designated Comprehensive Cancer Center, Rutgers Cancer Institute of New Jersey. Rutgers University 05/2000 - 05/2006 Tenure-track Assistant Professor (2000), and tenured Associate professor (07/2003), Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM 05/1997 - 05/2000 Tenure-track Assistant Professor, Cancer Center and Department of Molecular Genetics, University of Illinois at Chicago, Chicago, IL. 09/2016 – 05/1997 Staff Scientist, Los Alamos National Laboratory, New Mexico, USA Selected Professional Services 2001 – 2005 Panel member of Tumor Biology Study Section (3 times), the Susan G. Komen Breast Cancer Research Foundation 2003 – 2016 panel members (>10 times), various study sections for DOD Breast Cancer Research Program, Prostate Cancer Research Program, Ovarian Cancer Research Program, and Lung Cancer Research Program (details of the panel omitted per DOD policy) 2004 - 2009 NIH Cancer Etiology study section: ad hoc member (3 times), and standing member (2005-2009) 2005 – 2020 NIH Radiation Therapeutics and Biology (RTB) study section: ad hoc member (9 times), and standing member (2016-2020) 2007 – 2013 member, various NIH special panels on F- and K-series fellowship and career awards (>17 times). 2014 - 2016 NCI selected panels for P01 projects (3 times) 2015 – 2017 Chairperson (3 times), DOD BCRP and OCRP Scientific Review Panels (details of the panel omitted per DOD policy) 7 Election Candidates 2011 2013 2011 - 2020 2015 - Guest editor, Journal of Molecular and Cellular Biology, special issue on “Genomic Instability 2013 and Cancer”, Guest editor, Cell & Bioscience (the official journal of SCBA), special theme issue on “Cancer Biomarkers and Targeted Therapies”. Associate editor, Journal of Molecular and Cellular Biology Editorial board member, Cell & Bioscience (the official journal of SCBA). Research Interests: Our longstanding interests are elucidating the mechanisms by which genomic instability is induced and how it drives tumorigenesis. We focus on mammalian homologous recombination and its associated cellular processes that contribute to error-free DNA repair and replication fidelity. Using a BRCA2 interacting protein BCCIP as the platform, we strive to understand how DNA replication and recombination dysfunctions during S-phase may contribute to mitotic chromosome instability. We extensively use genetically engineered mouse models to understand the confounding roles of cell growth essential genes involved in the maintenance of genomic integrity in distinct stages of tumorigenesis such as tumor initiation and progression. SCBA Service Statement: I joined SCBA in 2002 as a lifetime member. In the past, I have organized (and served as the co-chair of) several scientific sessions and attended most of the bi-annual SCBA meetings since 2002. In 2013, I was invited to serve as a guest editor for a special issue of “Cancer Biomarkers and Targeted Therapies” on the official SCBA journal of Cell & Biosciences, and became an editorial board member of the journal in 2015. I have served as a scientific reviewer in multiple capabilities, including as study section chairs for US DOD breast and ovarian cancer research programs, and NSF of China. As a division chief, and a program leader of NCI designated comprehensive cancer center, I am also an experienced academic administrator. If elected to the SCBA Nomination Committee, I will use my scientific expertise and leadership skills to promote the recognitions of the diverse range of scientific achievements by our members. NOMINEES FOR SCBA COUNCILOR MINGYAO LIU, MD, MSc Current Position: Professor of Surgery, Medicine and Physiology Director, Institute of Medical Science Faculty of Medicine, University of Toronto (UT) Senior Scientist, Head of Respiratory and Critical Care Research Toronto General Hospital (TGH), University Health Network (UHN) Education and Training: M.D., 08/1978-08/1983 Medicine, Second Military Medical University M.Sc., 09/1983-08/1986 Pathophysiology, Second Military Medical University 07/1990-03/1994 Research Fellow, SickKids Research Institute, Toronto, Canada Previous Positions: 02/1988-06/1990 Assistant Research Professor, State University of New York at Buffalo 10/1994-06/2000 Assistant Professor, University of Toronto 04/1996-05/2001 Staff Scientist, Toronto General Hospital Research Institute 07/2000-06/2004 Associate Professor, Depts. of Surgery, Medicine and Physiology, UT 09/2000-06/2005 Coordinator for Graduate Education, Institute of Medical Science, UT 06/2001-present Senior Scientist, TGRI, UHN 8 07/2004-present 07/2005-06/2007 07/2005-07/2011 07/2007-06/2010 07/2012-06/2014 07/2014-12/2014 01/2015- present Election Candidates Professor, Depts. of Surgery, Medicine and Physiology, UT Associate Dean (Life Science), School of Graduate Studies, UT Director, Center for Research Education and Training, UHN Director, International Research Relations, Faculty of Medicine, UT Associate Director, Institute of Medical Science, Faculty of Medicine, UT Interim Director, Institute of Medical Science, Faculty of Medicine, UT Director, Institute of Medical Science, UT 2013 Research Interests: My research is to study the cellular and molecular mechanisms of acute lung injury, especially in lung transplantation. We demonstrated that lung epithelial cells as a source of cytokines in inflammatory response, intracellular signal transduction pathways as therapeutic targets, and roles of multiple cell death pathways in acute lung injury. We have developed nanoparticle based drug delivery systems. A drug discovery/delivery pipeline has been developed, including cell culture for high throughput screening for therapeutic targets, mouse/rat lung transplant models for in vivo testing, and pig lung transplant and ex vivo lung perfusion system for pre-clinical trials. We also discovered a novel adaptor protein, XB130, for signal transduction, and demonstrated its role in cell survival, proliferation, migration and regulation of gene expression. Using xb130 knock mice, we are studying the role of XB130 in lung injury and repair. Previous services to SCBA: Member, Society of Chinese Bio-Scientists in America, 1998-present Member, Executive Committee, SCBA Toronto Chapter, 2000 – 2005, 2008-present President, SCBA Toronto Chapter, 2001-2003 Chair, Second SCBA/CCABP Scientific Symposium, Scientific Program, 2001, 2002, 2008 Member, SCBA International Conference, Scientific Program Committee, June 2002-July 2004 Co-Chair, SCBA International Conference, Workshop Beijing, China, July 19 2004 Member, Membership Committee, Society of Chinese Bio-Scientist in America, 2007-2010 SCBA Toronto Chapter Scientific Symposium Organization Committee, Member 2002 - 2005, 2009-2017 Selected Accomplishments and Honours: 2000-2005 Premier's Research Excellent Award, Ontario, Canada 2006 Mel Silverman Mentorship Award, Institute of Medical Science, UT 2013 Queen Elizabeth II Diamond Jubilee Medal, Government of Ontario WEI YANG, Ph.D. Current Positions: Distinguished Investigator & Chief of Structure and Mechanism Section Laboratory of Molecular Biology, NIDDK National Institutes of Health Education and training: B.A., Biochemistry, SUNY at Stony Brook (NY), 1985 Ph.D., Biochem. & Mol. Biophys, Columbia University (NY), 1991 Postdoc fellow, Columbia University (NY), 1991-2 Postdoc fellow, Yale University (CT), 1992-5 Previous Positions: 1995 - 2000 Tenure-track group leader, NIDDK, NIH 2000 – 2004 Tenured investigator, NIDDK, NIH 9 2004 – present 2016 – present 2004 – 2015 Election Candidates Section Chief, NIDDK, NIH Distinguished Investigator, NIDDK, NIH Adjunct professor at Johns Hopkins Medical School 2013 Research Interest: My lab investigates DNA translesion synthesis, mismatch and excision repair, and V(D)J recombination. We discovered the ATPase activity of MutL, the proofreading function of the MutS ATPase, and the mechanochemical coupling nature of ATP hydrolysis in a molecular motor. While studying mechanisms of cancer avoidance by translesion DNA polymerases, recently we have discovered the three-metal-ion mechanism in nucleic acid synthesis and degradation. Past services to SCBA: President Baltimore-Washington DC SCBA Chapter, 2013-2014 Selected Honors and Awards: The 2002 Bea Singer Young Investigator Award (sponsored by the GRC) The 2011 Dorothy Crowfoot Hodgkin award (sponsored by the Protein Society) American Association for the Advancement of Science (AAAS) fellow, since 2012 National Academy of Sciences (NAS), member since 2013 American Academy of Arts and Sciences (AAAS), member since 2015 SCBA Presidential Award, 2015 The 2017 Mildred Cohn Award in Biological Chemistry (sponsored by ASBMB) Jing Zhou, M.D., Ph.D. Current Positions: Director, Laboratory of Molecular and Developmental Genetics Founding Director, Harvard Center for Polycystic Kidney Research Professor of Medicine Brigham and Women's Hospital and Harvard Medical School Chair of the Board of Directors of Chinese American Society of nephrology Past President of Chinese American Society of nephrology Education and Training: 1983 M.D. Equivalent, General Medicine, Shanghai First Medical College, Shanghai, China 1992 Ph.D. Molecular Genetics, University of Oulu, Oulu, Finland 07/82-06/83 Intern, Internal Medicine, Surgery, Pediatrics, Obstetrics, Psychiatry, Various hospitals affiliated with Shanghai First Medical College Positions: 1983-1989 1989-1990 1991-1992 1992-1993 1993-present 1993-1998 Resident, Department of Internal Medicine, Peoples Hospital of Zhejiang Province, China Research Assistant, Department of Biochemistry, University of Oulu, Finland Research Assistant, Finnish Academy, Oulu, Finland Associate Research Scientist, Department of Medicine, Yale University School of Medicine, New Haven, CT Associate Physician, Brigham and Women's Hospital, Boston, MA Assistant Professor of Medicine, Harvard Medical School, Boston, MA 10 1998-2016 1999-present 2005-present 07/11-present 2016-present Election Candidates Associate Professor of Medicine, Harvard Medical School, Boston, MA 2013 Member, Department of Genetics, Biological and Biochemical Science Program, Harvard Medical School Director, Harvard Center for Polycystic Kidney Disease Research Member, Affiliated faculty, Harvard Stem Cell Institute Professor of Medicine, Harvard Medical School, Boston, MA Research Interest: I have studied inherited kidney diseases for 27 years. After practicing medicine for six years, I moved to Finland and started research by cloning the first kidney disease gene (Alport syndrome) (Science). At Yale, I cloned another basement membrane collagen gene and showed its disease association (Science). In 1993, I established my lab at BWH, and began biochemical and transcriptional studies of type IV collagen and Alport syndrome. I expanded my interest to clone PKD genes in 1994 and started to focus on PKD in 1998. I have devoted my time largely to laboratory research, as well as training research and clinical fellows and graduate and undergraduate students in the lab. We have created the first targeted mouse model for PKD, and generated over ten conventional, conditional, and inducible mouse models for both dominant and recessive forms of PKD—which led to the understanding of a critical role for PC1 in multiple organ development, injury, and repair (Nature Genetics). We identified four novel members of the polycystin family (Nature). We were first to demonstrate that polycystins are Ca2+-permeable cation channels, that PC1 acts as a G-protein coupled receptor, and that PC1 and PC2 mutually regulate each other’s function. We showed the first evidence of PC1 and PC2 function on primary cilia and Ca2+ signaling (Nature Genetics). We identified other disease proteins—including ARPKD, nephronophthisis, and Bardt Biedl syndrome proteins—as components of the primary cilia and/or polycystin network, and showed that polycystins regulate the cell cycle, planar cell polarity, cell migration, and actin cytoskeleton integrity. Our current efforts are to elucidate the polycystin protein network, and to develop PKD therapeutics by balancing the network using mouse models. Selected Honors: 1992 Excellent Graduate Student Fellowship, University of Oulu, Oulu, Finland 2000 Young Investigator Award, American Heart Association and American Society of Nephrology. First woman in 17 years to receive this award 2003 Rated as Author of one of the three Fast Breaking Papers in field of Molecular Biology and Genetics in by ISI Essential Science Indicators 2005-present Elected member, American Society of Clinical Investigation 2005-2016 MERIT (Method to Extend Research in Time) Award, NIDDK, NIH 2007 Lillian Jean Kaplan International Prize, Lifetime achievement Award Jointly awarded by the International Society of Nephrology, Lillian Jean Kaplan Foundation and the Polycystic Kidney Disease Foundation in Rio Brazil. First woman to receive this Award 2007 Distinguished Service Award, Chinese American Society of Nephrology 2015 Keynote Lecture of the First International Congress of Chinese Nephrologists and Annual Scientific Meeting of Hong Kong Society of Nephrology, Hong Kong, China 2015 Chan Woon Cheung Award, Hong Kong Society of Nephrology 2015 Honors Award, International Society of Nephrology and American Nephrologists of Indian Origin 2016 Honorary Master Degree, Harvard University Other Professional Positions 2001Honorary Professor, Zhejiang University, Zhejiang, China 2001-2008 Scientific Advisory Board, Polycystic Kidney Disease (PKD) Foundation 2002-present Board of Directors, Chinese American Society of Nephrology 2002-2004 Member of Board of Directors, Chinese American Society of Nephrology 2004-2006 President, Chinese American Society of Nephrology 2012-present Executive Director/Chair of Board, Chinese American Society of Nephrology 2002-2008 Board of Directors, Newton Chinese Language School 2002-2003 General Medicine B Study Section, NIH 11 Election Candidates 2004-2006 Permanent member, Cellular and Molecular Biology of the Kidney Study Section, NIH 2013 2009KUH Fellowship Review Study Section, NIDDK, NIH 2010, 2012, 2013, 2014 Special Emphasis panel, NIDDK, NIH 2006Advisor of Academic Committee, Chinese Institute of Nephrology, Shanghai, China. 2007 Member, Core Scientific Program Committee, World Congress of Nephrology meeting in Rio, Brazil 2010-2011 Member, Program Committee, 44th Annual Meeting of American Society of Nephrology, Philadelphia, PA (organized 5 Symposia, 3 free communication sessions, and 4 poster sessions) 03/14-02/17 Qiushi Professor (non voting), Medicine, Zhejiang University, Zhejiang, China 2015 Honorary Professor, People’s Hospital of Zhejiang Province I have given over 100 invited lectures in national and international meetings and institutions, and served as session chair or organizers at over 30 national and international meetings. YIMIN ZOU, Ph. D. Current Positions Professor and Chair Neurobiology Section Biological Sciences Division University of California, San Diego Education and Training B.S., Genetics, Fudan University, China 1988 Ph.D., Biochemistry and Molecular Biology, University of California, San Diego and Davis, 1995 Postdoctoral Fellow, Developmental Neuroscience, University of California, San Francisco, 2000 Previous Positions 2000-2006 Assistant Professor, Department of Neurobiology, the University of Chicago 2006-2006 Associate Professor (with tenure), Department of Neurobiology, the University of Chicago Associate Professor, Neurobiology Section, University of California, San Diego 2006-2011 2011-present Professor, Neurobiology Section, University of California, San Diego 2012-2014 Vice Chair, Neurobiology Section, University of California, San Diego 2014-present Chair, Neurobiology Section, University of California, San Diego Research Interest My lab studies molecular and cellular mechanisms of axon guidance, synapse formation, and assembly, stability and regeneration of neural circuits. We identify molecular guidance cues that provide directional information for axon wiring in vivo as well as signal transduction pathways and cell biological mechanisms underlying growth cone turning. We also study synaptogenesis and how specific synaptic connection patterns emerge from the interplay of molecular guidance system and neural activity. We are interested in how central nervous system responds to traumatic injury and develop therapeutic approaches to promote axonal and neuronal survival to combat degenerative disorders and improve axon regeneration and functional recovery following spinal cord injury. Selected Honors and Awards, and non-SCBA Services 1989-1993 CUSBEA Fellowship 1993-1995 Institutional Predoctoral NRSA, NIH 1995-1996 Institutional Postdoctoral NRSA, NIH 1996-1998 Individual Postdoctoral NRSA, NIH 1999-2000 Postdoctoral Fellowship from the Spinal Cord Research Foundation 2002-2005 Schweppe Foundation Career Development Award 2002-2004 March of Dimes Basil O’Connor Starting Scholar Research Award 2003-2005 Alfred P. Sloan Research Fellow Award 12 2003 2005 2006 2006 2008 2009 2011 2011 2012 2012 2013 20132013 2013-2016 2014 2015 2016 2017 Election Candidates W. M. Keck Foundation Research Achievement Award (Semi-finalist in Keck Young Scholar 2013 Competition) Chair of “Minisymposium on Wnt Signaling in Neural Circuit Development” at Society for Neuroscience Meeting. Washington, DC. Gail Beach Memorial Seminar Series at the University of Miami Miller School of Medicine, Miami, Florida Keynote Speaker at Midwest Student Biomedical Research Forum. Omaha, Nebraska. Chair of “Symposium on Genetic determinants specifying neuronal connections” at Society for Neuroscience Meeting. Washington, DC. Killam Research Seminar the Montreal Neurological Institute McGill University. Montreal, Canada. Chair of Symposium Organizer: Signaling and cell biological mechanisms of growth cone guidance at 8th IBRO World Congress of Neurosciences. Florence Italy Organizer of Cold Spring Harbor Asia Meeting on Neural Circuits. Suzhou China S. T. Huang-Chan Memorial Lecture Hong Kong University, Hong Kong, China 北京生科院精品讲座 Organizer of Cold Spring Harbor Asia Meeting on Neural Circuits. Suzhou China Member and Secretary of Board of Directors of Ray Wu Memorial Fund and CBIS Director’s Seminar Series (贝时璋讲座)Institute of Biophysics, CAS Honorary Professor of the University of Hong Kong Dean’s Seminar Series (院长讲座)Peking University Medical School AbCam Meeting on Frontiers of Signaling. Shanghai, China. Co-Organizer of Cold Spring Harbor Asia Meeting on Neural Circuits. Suzhou China Co-Organizer of Keystone Symposium on Neural Circuits, Colorado CANDIDATES FOR NOMINATION COMMITTEE WENYI WEI, Ph.D. Current Positions: Associate Professor, Dept. of Pathology Beth Israel Deaconess Medical Center, Harvard Medical School Education and training: B.A., Shandong University, Jinan, China, 1993 M.S. Chinese Academy of Sciences, Beijing, China, 1996 Ph.D. Brown University, Providence, R.I., 2002 Postdoctoral fellow, Dana-Farber Cancer Institute, Harvard Medical School, 2002-2006 Previous Positions: 2006-2012 Assistant Professor, Dept. of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 2012Associate Professor, Dept. of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 2015Director, Biochemistry Program, BIDMC Cancer Center and Cancer Research Institute, Boston, MA Research Interests: Aberrant cell cycle regulation leads to various human disease including cancer and cardiovascular disorders. Proper cell cycle transitions are driven by waves of ubiquitin-dependent degradation of key cell cycle regulators by APC or SCF, the two major E3 ligase complexes. The major focus of research in my laboratory is aimed at understanding how APC and SCF activities contribute towards cell cycle regulation and subsequent tumor formation. More specifically, I am interested in elucidating the 13 Election Candidates underlying mechanisms that define the oscillation of APC and SCF activity in different cell cycle phases. To achieve these 2013 goals, my lab will use multidisciplinary approaches including biochemical and genetic analysis. In the long term, I hope that a better understanding of the multilayer regulation of the delicate proteolysis pathways will lead us to the design of more efficient intervention strategies to combat cancer, cardiovascular disorders and other human diseases. Previous services to SCBA: 2015, Session co-Chair, 15th SCBA International Symposium, Taipei, Taiwan. 2016, Session co-Chair, 16th SCBA International Symposium, Hangzhou, P.R. China. Life-time member since 2017. Selected Honors and Awards, and non-SCBA services: 2005-2008 Special Fellow, the Leukemia & Lymphoma Society 2007-2009 Emerald Foundation Award for New Investigator 2007-2009 Kimmel Scholar 2008-2010 V Scholar 2009-2012 Department of Defense Prostate Cancer Program New Investigator Award 2009-2012 Massachusetts Life Science Center New Investigator Award 2011-2013 BIDMC Prostate Research Program New Investigator Award 2012-2016 American Cancer Society Research Scholar 2013-2018 Leukemia and Lymphoma Society Research Scholar 2015 Elected Fellow, American Association for the Advancement of Science (AAAS) Editorial Board Member for: 2010American Journal of Cancer Research 2011Molecular and Cellular Biology 2012Cancer Hallmarks 2013Cancer Research 2013Journal of Biological Chemistry 2015Scientific Reports ZHONG-PING FENG, MD, Ph.D. Current Position Professor (Tenured) & Graduate Coordinator, Physiology Director, Collaborative Program In Neuroscience Member, Academic Board of the Governing Council University of Toronto Treasurer, Canadian Physiological Society Executive Committee Member, SCBA Toronto Chapter Education & Training (Completion Year): 1983 Medical Degree, Zhongshan Medical College, Guangzhou, China (Medicine) 1984, Residency, Peking Union Medical College Hospital (Capital Hospital), Beijing, China (one year internship 06/82 to 07/83) (Ophthalmology) 1989 MSc, University of Alberta, Edmonton, Canada (Pharmacology) 1998 PhD, University of Calgary, Calgary, Canada (Neuroscience) 2002 Post-doctorate, University of Calgary, Calgary, Canada (Physiology/Biophysics) 14 Election Candidates Previous Positions 2003 Assistant Professor, Department of Physiology, University of Toronto, Toronto, Canada 2008 Associate Professor (Tenured), Department of Physiology, University of Toronto, Toronto 2013 Research Interests: Dr. Feng’s laboratory 1) investigates the biophysical and pharmacological properties of ion channels, 2) determines calciumdependent regulatory mechanisms of neurodevelopment, neural plasticity, neurodegeneration and neuroregeneration, and 3) identifies and characterizes drug targets from for neurodevelopmental and neurodegenerative disorders. She has published over 110 research articles and reviews, and one United States patent. Selected Awards: Dr. Feng has received research grants and personal awards from NSERC, CIHR, HSFC, and CFI. She was a recipient of the Premier’s Research Excellence Award from the Ontario Government, CIHR New Investigator and HSF New Investigator, The Boehringer Ingelheim Young Investigator Award, Bright Lights Award from Firefly Foundation. She has been awarded with Connaught New Faculty Award, Faculty of Medicine Dean’s Fund New Faculty Award, Breaking the Glass Ceiling Award from Women in Science and Engineering (WISE), Graduate Student Mentorship Award from Faculty of Medicine, and Innovative Course Design Award and Excellence in Teaching Performance from Department of Physiology, at University of Toronto. Previous services to SCBA: Present-elected, President, and Past-President, Toronto Chapter, SCBA (2009 – 2013) Executive Committee member, Toronto Chapter, SCBA (2014 – present) Chair, Ion Channel Symposium, SCBA Conference (2010) Guangzhou, China Organized and hosted several SCBA Toronto Chapter dinner events Participant of past SCBA meetings HUILIN ZHOU, Ph.D. Current Position: Associate member, Ludwig Institute for Cancer Research Professor, Department of Cellular and Molecular Medicine, University of California, San Diego, CA Education and Training: B.S. University of Science and Technology of China, Hefei, P.R. China, 1991 Ph.D. Stanford University, Palo Alto, CA, 1998 Postdoc fellow, Institute for Systems Biology and University of Washington, Seattle, WA, 2002 Research Interests: Our research program focuses on understanding the signaling pathways that maintain genome integrity, including the DNA damage checkpoint and protein sumoylation. Genetic studies in the yeast Saccharomyces cerevisiae have established a major role of DNA damage checkpoint kinases in suppressing gross chromosomal rearrangements (GCRs), a hallmark of human cancers. We have developed quantitative phospho-proteomics to identify and characterize substrates of DNA damage checkpoint kinases and investigated the regulation of the DNA damage checkpoint kinase cascade. More recently, we have discovered that SUMO E3 ligases have a major role in suppressing non-allelic homologous recombination mediated chromosomal translocations. We have developed quantitative mass spectrometry based assay to measure intracellular protein sumoylation on a proteome-wide scale, and used this approach to develop a comprehensive view of the enzyme-substrate 15 Election Candidates relationship in the SUMO pathways, including SUMO E3 ligases that catalyze the attachment of SUMO to its substrates as 2013 well as SUMO isopeptidases that cleave SUMO off its targets. Our current studies focus on the role of protein sumoylation in diverse areas of chromosome biology, including DNA replication, gene silencing and chromosome segregation. We are further extending our findings using yeast as a model system to human cells and study the conservation of the underlying molecular mechanisms and their relevance to cancer etiology. Selected honors and previous service to SCBA: The NHGRI Genome Scholar Development and Faculty Transitional Award, 2002-2005. Participants/speakers of past SCBA meetings. Nomination committee since 2013 YANG LIU, PhD Director, Center for Cancer and Immunology Research, Bosworth Chair Professor for Cancer Biology and Immunology, Children’s Research Institute, Children’s National Medical Center, George Washington University, Washington, DC A. Research Interest My laboratory studies the fundamental mechanism of immune recognition and cancer biology. We have been a driving force in elucidating the mechanism by which the innate immune system discriminates microbial infection and aseptic tissue injuries in the last decade, we have devoted a major effort to studying the basic mechanism of tumorigenesis. We pioneered the concept of an X-linked tumor suppressor gene and established a surprisingly critical role for, and therapeutic targeting of, hypoxia-inducible factor in the function of stem cells in hematological malignancies. The cross-fertilization between studies on immune recognition and tumor biology allowed us to develop a novel approach that enables the immune system to recognize cancer without the constraints imposed by mechanisms evolved to tune down innate immunity to tissue injuries. B. Past Positions 1992--1996 Assistant Professor, Department of Pathology, New York University School of Medicine, New York, NY 1996--1998 Associate Professor with tenure, Department of Pathology, New York University School of Medicine, New York, NY The Kurtz Chair Professor of Pathology, Department of Pathology, Ohio State University Medical Center, 1998-2006 Columbus, OH 2001-2006 Director, Division of Cancer Immunology, Department of Pathology, Ohio State University Medical Center, Columbus, OH 2003--2006 Immunology Program Co--Leader, Comprehensive Cancer Center, Ohio State University, Columbus, OH 2006--2010 Professor and De Nancrede Chair, Director, Division of Immunotherapy, Departments of Surgery, Internal Medicine and Pathology, Co-leader, Immunology Program, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI 2010--2011 President, CBIS Director, Center for Cancer Immunology Research, Bosworth Chair Professor for Cancer Biology and Immunology, Children’s Research Institute, Children’s National Medical Center, George Washington University, Washington DC Honors 1990 1992 1992 2004 2011 Irvington Fellowship Markey Scholar Award Searle Scholar Award AAAS Fellow League of Research Excellence, University of Michigan 16 2014 Election Candidates Snyder Award for outstanding cancer research, George Washington University 2013 Past service to SCBA: Nomination committee in 1990s. XIAO-JING WANG, M.D., Ph.D. Professor, Department of Pathology John S. Gates Endowed Chair of Cancer Stem Cell Biology Director, Head and Neck Cancer Research Program, University of Colorado Anschutz Medical Campus Tel. (303) 724-3001; fax. (303) 724-3712 Email: XJ.Wang@ucdenver.edu EDUCATION 1984 M.D., Beijing Medical University, Beijing, China 1989 Ph.D. (Neuroscience), Beijing Medical University, Beijing, China 1991 Postdoctoral fellow, MD Anderson Cancer Center, TX BRIEF CHRONOLOGY OF EMPLOYMENT 1992-1994 Research Associate, Department of Cell Biology, Baylor College of Medicine, Houston, TX 1994-1995 Research Instructor, Department of Cell Biology, Baylor College of Medicine, Houston, TX 1995-1999 Assistant Professor, Departments of Cell Biology, Dermatology, Baylor College of Medicine, Houston, TX 2000-2002 Associate Professor (tenured), Departments of Dermatology, Molecular & Cellular Biology, Baylor College of Medicine, Houston, TX Professor (tenured), Director, Molecular Biology-Head and Neck Cancer Research Division, Department of Otolaryngology, Oregon Health & Science University, Portland, OR Professor, Departments of Cell & Developmental Biology, Dermatology. 2008-present Professor, Depts of Pathology, Otolaryngology, Dermatology, SOM; Dept. of Craniofacial Biology, SOD RESEARCH INTERESTS AND EXPERTISE: · TGFβ signal transduction · Functions of tumor suppressors and oncogenes · Skin development, wound healing and diseases PAST SCBA SERVICES · Life-time SCBA member · 2005-2007: President SCBA Oregon Chapter · Session co-chairs for SCBA meetings 2011, 2013, 2015, 2017. SELECTED NATIONAL/INTERNATION PROFESSIONAL ACTIVITIES Scientific committee member for the Society of Investigative Dermatology, 2005-10. Scientific committee Chair for the Society of Investigative Dermatology, 2009-2010. Board Member, Chinese Biological Investigator Society, 2010-2014 Ad hoc Board of Scientific Counselor, National Cancer Institute, 2012, 2014 Advisory Council Member, NIAMS, 2012-2015 Executive Editor, International Journal of Biological Sciences Associate Editor, Molecular Carcinogenesis Associate Editor, Journal of Investigative Dermatology 17 Election Candidates 2013 NAN-PING WENG, M.D., Ph.D. Current Positions: Senior Investigator, Chief of Lymphocyte Differentiation Section, Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health Education and training: M.D. Shanghai First Medical College (Fu Dan Shanghai Medical College), China, 1984 Ph.D. Immunology, Baylor College of Medicine, TX 1993 Postdoctoral fellow, National Cancer Institute, MD, 1994-1997 Previous Positions: 1984-1987: Lecturer, Department of Forensic Pathology, Shanghai First Medical College 1997-2005: Tenure-track Investigator, Laboratory of Immunology, National Institute on Aging (NIA), NIH, Baltimore, MD 2006-2011 Senior Investigator, Chief of Lymphocyte Differentiation Section, Laboratory of Immunology, NIA, NIH, Baltimore, MD 2012-present Senior Investigator, Chief of Lymphocyte Differentiation Section, Laboratory of Molecular Biology and Immunology, NIA, NIH, Baltimore, MD Research Interest: My laboratory has a longstanding interest in mechanisms of immune system aging. We focus on three areas: 1) role of telomere and telomerase in T cell function and aging, 2) general and antigen-specific ab TCR repertoires and the impact of their change with aging on immune function, and 3) molecular mechanism of memory T cell formation, maintenance, and aging with emphasis on transcription and epigenetic regulation. We conduct our studies in human using the participants from the Baltimore Longitudinal Study on Aging (BLSA) and in various genetically modified mouse models. Our studies have shown that 1) the in vivo dynamic changes of telomere length in lymphocytes and monocytes with age as well as age-related decline of telomerase activity in T and B lymphocytes; 2) distinct features of general and anti-viral ab TCR repertoires in human; and 3) epigenetic regulation of differential gene expression in naïve and memory CD8 T cells. Past services to SCBA Session Chair, 15th SCBA International Symposium Session Chair, 1st SCBA Baltimore-Washington Chapter Symposium Selected Honors and Awards, and non-SCBA services: 1994 NIH Fellows Award for Research Excellence 1998-2004, 2010, and 2013 NIA Staff Recognition Award for Exemplary Contributions 2007 NIH Postbac IRTA Committee in recognition of the outstanding contributions to the education and guidance of the Postbac trainees. 18 Election Candidates CANDIDATES FOR MEMBERSHIP COMMITTEE XUE SEAN LI ( ), PHD Current Positions Associate Professor Department of Surgery, and Urology Boston Children’s Hospital Harvard Medical School Boston, MA 02115, USA Education Henan College of Food Science, Zhenzhou, Henan, China Mount Sinai School of Medicine, New York, NY, USA. Ph.D. (1997) University of California, San Diego, CA, USA. Postdoctoral Fellow Appointments 2002-2005 20052005-2015 2015- Assistant Research Scientist, School of Medicine University of California, San Diego Staff Scientist, Departments of Surgery/Urology Children’s Hospital Boston, Boston, MA Assistant Professor, Department of Surgery Harvard Medical School, Boston, MA Associate Professor, Department of Surgery/Urology Harvard Medical School, Boston, MA Research Interest We are interested in the sex differences in development and cancer. There are several ongoing NIH-sponsored projects, which include the sex differences in bladder cancer incidence and mortality, the sexually dimorphic mechanisms of genital tubercle differentiation, the epigenetic basis of urinary tract infection and inflammation, and congenital heart disease related to the outflow tract formation. Past Service to SCBA I am currently serving as president of the Boston Biology and Biotechnology (BBB), a professional association of Chinese Principal Investigators at the great Boston area. We are current working with the leaderships of BBB and SCBA aiming to establish a local SCBA chapter at the New England area. Selected Honors NRSA postdoctoral award, NIH/NIDDK Career Development Award, Basil O’Connor Scholar, Eleanor and Miles Shore Scholar, Carl W. Gottschalk Research Scholar 19 2013 Election Candidates Ji#Luo#Ph.D.# ! Current#Position# Investigator! National!Cancer!Institute,!NIH! ! Education#and#Training# 2006! –! 2010:! Postdoctoral! fellow,! Department! of! Genetics,!Harvard!Medical!School,!Boston,!MA!! 2006:! Ph.D.! in! Cellular! and! Development! Biology,! Harvard!University,!Boston,!MA!! 1998:!B.A.!in!Natural!Sciences,!University!of!Cambridge,! Cambridge,!UK!! ! Research#Interest# My! research! focuses! on! understanding! the! biology! of! epithelial! cancer! driven! by! the! Ras! oncogene.! We! are! applying! RNAi! and! CRISPRPbased! genetic! approaches! to! dissect! functional! dependencies! and! mechanisms! of! nonPoncogene! addiction! in! Ras! mutant! cells.! My! lab! is! currently! investigating! how! various! Ras! effector! pathways! and! protein! postPtranslational! modification!pathways!contribute!to!the!malignant!phenotype!of!KRAS!mutant!cancer!cells.!In! addition,!we!are!developing!new!RNAi,!CRISPR!and!pharmacological!platform!for!target!validation! and!lead!discovery!for!Ras!mutant!cancer.!! ! Past#Services#to#SCBA# 2016!–!present:!Treasurer,!SCBA!DCPBaltimore!Chapter! 2016:!SCBA!DCPBaltimore!Chapter!2nd!Annual!Symposium!meeting!coPchair! 2014P2015:!SCBA!DCPBaltimore!Chapter!Workshops! ! Selected#Honors#and#Awards,#and#nonASCBA#Services# 2014:!NCI!Annual!Intramural!Scientific!Retreat!Research!Highlights!Award! 2011:!NCI!Director’s!Intramural!Innovation!Award 2008:!AACR!AstraZeneca!postdoctoral!fellowship!in!translational!lung!cancer!research!! 2010!–!2015:!CoPchair,!TenurePTrack!Investigator!Committee,!NCIPCCR!! 2011!–!2015:!CoPOrganizer,!TenurePTrack!Investigator!Chalk!Talk!Seminars,!NCIPCCR!! 2011!–!2015:!CoPorganizer,!TenurePTrack!Investigator!Annual!Retreat,!NCIPCCR!! ! ! ! ! 20 2013 Election Candidates 2013 Li Yang, Ph.D. Current position: Senior Investigator, Head, Tumor Microenvironment Section, Laboratory of Cancer Biology and Genetics, National Cancer Institute Education and training: 2004-2008 Postdoc, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine. 2000-2004 Ph. D., Department of Cancer Biology, Vanderbilt University 1983-1986 M.S., Developmental Biology and Cell Biology, Wuhan University, China 1979-1983 B.S., Biology, Sichuan University, China Research Interest: My research program focuses on molecular mechanisms underlying tumor-stroma interaction in cancer metastasis. We demonstrated that cancer-associated inflammation is critical in the functional switch of TGF-β from a suppressor to a promoter. We are currently investigating how myeloid-specific TGF-β signaling modulates host inflammation/immune response in cancer and stroke. We continue to understand roles of inflammation in the premetastatic environment in cancer cell colonization using molecular biology, cancer biology, as well as integrated genomic-wide genetics and epigenetics approaches. Past and Future Service to SCBA President elect, 2018, DC-Baltimore Chapter Organizer, 2017 DC-Baltimore Chapter scientific symposium Session Chair: 2016 Joint SCBA and CBA-MedImmune Annual Conference Honors and Other Special Scientific Recognition: 2016 Federal Technology Transfer Award, National Cancer Institute 2015 Co-recipient of FLEX Program Awards, NCI 2013 U.S.-China Biomedical Collaborative Research Award 2012 Federal Technology Transfer Award, National Cancer Institute 2004-7 Young Investigator Award and Career Development Award, Vanderbilt Ingram Cancer Center 21 ! Election Candidates ZHE$HAN,$Ph.D.$ $ Current$Position:$ Associate)Professor) Children’s)National)Medical)Center) Dept.)of)Pediatrics) George)Washington)University)School)of)Medicine) ) Education$and$Training:$ B.S.,)Peking)University,)1996) Ph.D.,)University)of)Michigan,)2002) Postdoc)Fellow,)UT)Southwestern,)2002K2006) ) Previous$Positions:$ 2006)K)2014,)Assistant)Professor,)Department)of)Internal) Medicine,) Department) of) Cell) and) Developmental) Biology,)University)of)Michigan)School)of)Medicine) 2014)K)present,)Associate)Professor,)Children’s)National)Medical)CenterO)Dept.)of)Pediatrics,) George)Washington)University)School)of)Medicine) ) Research$Interest:$ My)laboratory)has)a)longstanding)interest)in)genetic)diseases)affecting)heart,)kidney)and)blood.) We) use) Drosophila) and) cultured) human) cells) to) study) the) molecular) mechanisms) of) these) diseases.) My) lab) established) that) the) fly) heart) also) functions) as) a) filtration) kidney,) and) generated) the) first) fly) glomerular) kidney) disease) model.) Using) the) fly) heart) and) cardiac) nephrocytes,) we) discovered) the) molecular) mechanisms) of) several) congenital) heart) disease) (CHD))and)glomerular)kidney)diseases)caused)by)specific)genetic)mutations.)Most)recently,) we) developed) a) highKthroughput) validation) system) for) candidate) CHD) genes) in) flies,) and) demonstrated)that)85%)of)known)renal)disease)genes)play)conserved)roles)in)the)fly)kidney.) We)continue)to)be)interested)in)developing)personalized)fly)disease)models,)and)using)these) models)to)study)disease)mechanism)and)to)test)potential)drugs.)) $ Past$service$to$SCBA:$ Organizer,)SCBA)DCKBaltimore)Chapter)Annual)Symposium,)2017) ) Selected$Honors$and$Awards,$and$nonBSCBA$services:$ 2016) Renal)Grand)Round)Lecture,)Northwestern)University)) 2016) 11th)International)Podocyte)Conference)Lecture,)Israel) 2015) National) Institute) of) Health) (NIH),) National) Heart) Lung) and) Blood) Institute) (NHLBI),) Cardiovascular)Development)and)Differentiation)(CDD))Study)Section) 2014) NASA)International)Life)Science)Research)Program,)Review)Panelist)) 2006) University)of)Michigan)Biomedical)Sciences)Scholar) 2006) American)Heart)Association)National)Center,)National)Scientist)Development)Award) 2003) Pathways)to)Cardiac)Development)and)Regeneration)Conference,)Young)Investigator) Award) ) ) ! 22 2013 Election Candidates Dong Wang, Ph.D. Associate Professor University of California, San Diego Department of Cellular and Molecular Medicine, School of Medicine Divison of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences 9500 Gilman Drive, La Jolla, CA 92093-0625 Email: dongwang@ucsd.edu, Phone: (858) 822-5561, Fax: (858) 822-1953 Past Academic Position Jan., 2010 - July 2015 Education Oct., 2004 - Dec., 2009 Assistant Professor University of California San Diego, La Jolla, CA Postdoctoral Fellow, Department of Structural Biology School of Medicine, Stanford University, Stanford, CA Sept., 1999-Sept., 2004 Ph.D., Department of Chemistry Massachusetts Institute of Technology, Cambridge, MA Sept., 1993-June, 1998 B.S., Department of Chemistry Peking University, Beijing, P.R. China Honors and Awards 2015 OKeanos-CAPA Young Investigator Award at the Chemical and Biology Interface, Chinese-American Chemistry & Chemical Biology Professors Association (CAPA) 2012 - 2014 Kimmel Scholar Award, The Sidney Kimmel Foundation for Cancer Research 2008 - 2012 NIH Pathway to Independence Award (K99/R00) 2007 - 2008 Leukemia & Lymphoma Society Career Development Program Special Fellow Award 2002 - 2003 Anna Fuller Fund Graduate Fellowship Award 1996 Excellent Student in Honors Science Program, Peking University 1993-1995 Outstanding Student Scholarships at Peking University Research Interests Transcription and Epigenetic Regulation, Chromatin Remodeling, DNA Damage and Repair, Cancer Chemotherapy 23 2013 Election Candidates S.#Victor#HSIA,#Ph.D.# ! Current#Position:# Professor!and!Chair! Pharmaceutical!Sciences,!School!of!Pharmacy! University!of!Maryland!Eastern!Shore! ! Education#and#training:# ! # B.S.,!National!Taiwan!University,!1990! Ph.D.,!Wayne!State!University,!1999! Postdoctoral!Fellow,!NIH,!1999G2004! ! Previous#Positions:# ! 2004G2010:!Assistant!Professor,!Basic!Pharmaceutical!Sciences,!University!of!Louisiana!Monroe! 2010G2013:!Associate!Professor,!Pharmaceutical!Sciences,!University!of!Maryland!Eastern!Shore! 2013G2015:!Assoc.!Professor!and!Chair,!Pharmaceutical!Sciences,!University!of!Maryland!Eastern!Shore! 2015GPresent:!Professor!and!Chair,!Pharmaceutical!Sciences,!University!of!Maryland!Eastern!Shore! ! Research#Interest:# Molecular!and!cellular!mechanisms!of!herpesvirus!infections!! Thyroid!hormone!functions!! Novel!therapeutic!protocols!to!treat!viral!infections! ! Past#service#to#SCBA:# 2015:!CoGChair,!15th!SCBA!session!“New#roles#for#thyroid#hormone#in#metabolic#regulation#and#disease”! 2017:!Organizing!thematic!series!for!SCBA!journal!Cell!&!Bioscience!! ! ! Selected#Honors#and#Awards:# 2002:!NIH!Fellow!Associate!Research!Excellence!(FARE)!Award! 2006:!1st!Biennial!National!IDeA!Symposium!of!Biomedical!Research!Excellence!(NISBRE)!Poster!Award! 2009:!SCBA!Travel!Fellowship! 2011:!American!Association!of!Pharmaceutical!Scientists!(AAPS)!Annual!Meeting!Poster!Award! 2013:!University!of!Maryland!Eastern!Shore!Distinguished!Scholar! ! 24 2013 Election Candidates 2013 Boyi Gan, Ph.D. Current Position: Assistant Professor, University of Texas MD Anderson Cancer Center Elected Secretary, SCBA Texas Chapter Education and Training: 1993-1997, B.S., Microbiology, Fudan University, Shanghai, China 1997-2000, M.S., Genetics, Fudan University, Shanghai, China 2000-2006, Ph.D., Comparative Biomedical Sciences, Cornell University, Ithaca, NY, USA 2006-2010, Postdoctoral Fellow, Cancer Genetics, Dana-Farber Cancer Institute, Boston, MA, USA 2010-2011, Instructor, Cancer Genetics, Dana-Farber Cancer Institute, Boston, MA, USA Appointments: Nov, 2011- Tenure-track Assistant Professor, Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center 2012Member, The University of Texas Graduate School of Biomedical Sciences, Houston, TX Research Interests: Our lab studies the roles of energy sensing and metabolism in cancer. Specifically, we are interested in the questions: 1) how normal/cancer cells sense energy availability, 2) how cancer cell adapt to survive and grow under energy stress, and 3) how to translate our understanding of energy sensing/metabolism in cancer into novel effective cancer therapeutics. A deeper understanding of the biological processes linking energy sensing/metabolism to cancer will provide novel insight for cancer therapy and other diseases. SCBA Services: SCBA-Texas Chapter 2016-2017: Secretary (elected), SCBA-Texas Chapter Major responsibilities: a) In charge of Chapter communications, bi-weekly evening faculty research clubs, and other social activities; b) Participated in organizing the Chapter annual symposium consisting of plenary and keynote presentations, trainee presentations and judging, and election; c) Participated in organizing 2016 International Conference on Cancer and Immunology at Baoding co-hosted by SCBA-Texas Chapter and Hebei University. 2014-present: Member of the organizing committee of the SCBA-Texas annual symposium. National SCBA 2015: 2015 SCBA International Conference in Taipei Major responsibilities: Organize and chair a speaker session “the Regulation of Energy Metabolism in Human Diseases”. Non-SCBA Services and Leadership Positions: 2011-2016 Member, DOD Tuberous Sclerosis Complex Research Program (TSCRP) Review Panel 2015, 2016 Ad hoc member, NIH Study Sections 2015 Member, DOD Breast Cancer Research Program (BCRP) Review Panel 2011-2016 Member, MD Anderson Institutional Research Committee (IRG)-Basic Study Section Committee 2017Co-Chair, MD Anderson Institutional Research Committee (IRG)-Basic Study Section Committee 2017Member, MD Anderson Sister Institution Network Fund (SINF) Review Committee 25
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